지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 1 - 10 (10page)
이용수
초록· 키워드
오류제보하기
Background: We aimed to estimate whether elevated levels of complement C3a and C5a in amniotic fluid (AF) are independently associated with increased risks of intra-amniotic infection and/or inflammation (IAI) and spontaneous preterm delivery (SPTD) in women with cervical insufficiency or a short cervix (≤ 25 mm). Methods: We conducted a retrospective cohort study of 96 consecutive women with cervical insufficiency (n = 62) or a short cervix (n = 34) at 17 to 27 weeks, and who underwent an amniocentesis. AF was cultured and analyzed for C3a and C5a by enzyme-linked immunosorbent assay kits. The primary outcome measures were IAI (defined as a positive AF culture and/or an elevated AF interleukin-6 level [≥ 7.6 ng/mL]) and SPTD at < 32 weeks. Results: In multivariable analysis, AF level of C3a was the only variable significantly associated with IAI, whereas C5a level in AF and serum C-reactive protein level were not associated with IAI. Using SPTD at < 32 weeks as the outcome variable in logistic regression, elevated AF levels of C3a were associated with increased risk of SPTD at < 32 weeks after adjusting for other baseline confounders, whereas elevated AF levels of C5a were not. Conclusion: In women with cervical insufficiency or a short cervix, elevated AF level of C3a, but not C5a, is independently associated with increased risks of IAI and SPTD at < 32 weeks. These findings suggest that subclinical IAI or SPTD in the context of cervical insufficiency is related to activation of complement system in AF.
목차
등록된 정보가 없습니다.
참고문헌 (31)
참고문헌 신청
Lidegaard O / 1994 / Cervical incompetence and cerclage in Denmark 1980-1990. A register based epidemiological survey / Acta Obstet Gynecol Scand 73(1):35~38
Harger JH / 1983 / Cervical cerclage: patient selection, morbidity, and success rates / Clin Perinatol 10(2):321~341
조수현 / 2017 / Maternal Characteristics, Short Mid-Trimester Cervical Length, and Preterm Delivery / Journal of Korean Medical Science 32(3):488~494
Kuusela P / 2015 / Transvaginal sonographic evaluation of cervical length in the second trimester of asymptomatic singleton pregnancies, and the risk of preterm delivery / Acta Obstet Gynecol Scand 94(6):598~607
Romero R / 2006 / The role of cervical cerclage in obstetric practice: can the patient who could benefit from this procedure be identified? / Am J Obstet Gynecol 194(1):1~9
Harger JH / 1983 / Cervical cerclage: patient selection, morbidity, and success rates / Clin Perinatol 10(2):321~341
조수현 / 2017 / Maternal Characteristics, Short Mid-Trimester Cervical Length, and Preterm Delivery / Journal of Korean Medical Science 32(3):488~494
Kuusela P / 2015 / Transvaginal sonographic evaluation of cervical length in the second trimester of asymptomatic singleton pregnancies, and the risk of preterm delivery / Acta Obstet Gynecol Scand 94(6):598~607
Romero R / 2006 / The role of cervical cerclage in obstetric practice: can the patient who could benefit from this procedure be identified? / Am J Obstet Gynecol 194(1):1~9
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
The Identification of Immune-Related Plasma Proteins Associated with Spontaneous Preterm Delivery and Intra-Amniotic Infection in Women with Premature Cervical Dilation or an Asymptomatic Short Cervix
Journal of Korean Medical Science
2020 .01
-
Maternal Plasma and Amniotic Fluid LBP, Pentraxin 3, Resistin, and IGFBP-3: Biomarkers of Microbial Invasion of Amniotic Cavity and/or Intra-amniotic Inflammation in Women with Preterm Premature Rupture of Membranes
Journal of Korean Medical Science
2021 .11
-
Maternal Characteristics, Short Mid-Trimester Cervical Length, and Preterm Delivery
Journal of Korean Medical Science
2017 .01
-
Protective effect of low-intensity treadmill exercise against acetylcholine-calcium chloride-induced atrial fibrillation in mice
The Korean Journal of Physiology & Pharmacology
2022 .09
-
2021 대한부정맥학회 심방세동 환자의 새로운 접근법 및 통합적 관리 지침
대한내과학회지
2021 .10
-
Amniotic Fluid Infection, Cytokine Levels, and Mortality and Adverse Pulmonary, Intestinal, and Neurologic Outcomes in Infants at 32 Weeks’ Gestation or Less
Journal of Korean Medical Science
2017 .01
-
Prevalence of Atrial Fibrillation in Korean Population
International Journal of Arrhythmia
2017 .12
-
Risk Factor Management for Atrial Fibrillation
Korean Circulation Journal
2019 .01
-
Chronic Obstructive Pulmonary Disease Increases the Risk of New-onset Atrial Fibrillation and Mortality of Patients with Atrial Fibrillation
International Journal of Arrhythmia
2017 .12
-
Screening for Atrial Fibrillation Using a Smartphone-Based Electrocardiogram in Korean Elderly
전남의대학술지
2020 .01
-
Efficacy and Safety of Outpatient Clinic-based Elective External Electrical Cardioversion in Patients with Atrial Fibrillation
Korean Circulation Journal
2020 .01
-
2018 심방세동 카테터 절제술 대한민국 진료지침: Part I
International Journal of Arrhythmia
2018 .01
-
Prevalence of Nonnonevalvular Atrial Fibrillation Based on Geographical Distribution and Socioeconomic Status in the Entire Korean Population
Korean Circulation Journal
2018 .01
-
2021 대한부정맥학회 심방세동의 선별 검사 및 무증상 심방세동의 관리 지침
대한내과학회지
2021 .04
-
Clinical Implications of Preoperative Nonvalvular Atrial Fibrillation with Respect to Postoperative Cardiovascular Outcomes in Patients Undergoing Non-Cardiac Surgery
Korean Circulation Journal
2020 .01
-
Screening for Atrial Fibrillation Using a Single Lead ECG Monitoring Device
전남의대학술지
2021 .09
-
2018 대한부정맥학회 심방세동 환자의 통합적 관리 지침
대한내과학회지
2018 .01
-
심방세동을 가진 급성 허혈성 뇌졸중의 평균혈소판용적(mean platelet volume)의 상승
Journal of Neurocritical Care
2016 .01
-
2018 대한부정맥학회 비판막성 심방세동 환자의 뇌졸중 예방 지침
대한내과학회지
2018 .01
-
Incidence and Risk Factors for Atrial Fibrillation in Korea: the National Health Insurance Service Database (2002–2010)
Korean Circulation Journal
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0