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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 197 - 202 (6page)
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초록· 키워드
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Objective. This study examined the all-cause and sex-specific standardized mortality ratios (SMRs) in patients with spondyloarthropathy. Methods. Studies examining the all-cause and/or cause-specific SMRs in patients with psoriatic arthritis (PsA) and ankylosing spondylitis (AS) compared to the general population were surveyed using MEDLINE, EMBASE, and Cochrane databases and manual searches. A meta-analysis of the all-cause and sex-specific SMRs in patients with rheumatic diseases was then performed. Results. In total, 7 comparisons (5 PsA and 2 AS) from 6 reports met the inclusion criteria. Disease-specific meta-analysis showed that the pooled SMR was 1.299 (95% confidence interval [CI] 1.092∼1.605, p=0.015) for PsA and 1.784 (95% CI 1.576∼2.020, p＜0.001) for AS. Meta-analysis showed that the SMRs of PsA and AS were significantly higher (1.299 to 1.784 times) than those in the general population. The age- and sex-adjusted SMR was highest for AS (1.784), followed by PsA (1.299). Moreover, sex-specific meta-analysis showed that the all-cause SMRs were increased in female and male patients with PsA. On the other hand, mortality increased in male patients with AS (SMR 1.834), whereas there was no significant increase in female patients with AS. Conclusion. All-cause mortality is higher in patients with PsA and AS compared to the general population. On the other hand, the mortality was higher in males with AS but not in females.
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참고문헌 (19)
참고문헌 신청
Scarpa R / 2000 / Psoriatic arthritis: evolving concepts / Curr Opin Rheumatol 12:274~280
Brown MA / 2002 / Genetics of ankylosing spondylitis / Clin Exp Rheumatol 20(6 Suppl 28):S43~S49
Toledano E / 2012 / A meta-analysis of mortality in rheumatic diseases / Reumatol Clin 8:334~341
Lee S / 2010 / The burden of psoriatic arthritis: a literature review from a global health systems perspective / P T 35:680~689
Bakland G / 2011 / Increased mortality in ankylosing spondylitis is related to disease activity / Ann Rheum Dis 70:1921~1925
Brown MA / 2002 / Genetics of ankylosing spondylitis / Clin Exp Rheumatol 20(6 Suppl 28):S43~S49
Toledano E / 2012 / A meta-analysis of mortality in rheumatic diseases / Reumatol Clin 8:334~341
Lee S / 2010 / The burden of psoriatic arthritis: a literature review from a global health systems perspective / P T 35:680~689
Bakland G / 2011 / Increased mortality in ankylosing spondylitis is related to disease activity / Ann Rheum Dis 70:1921~1925
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