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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 222 - 226 (5page)
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초록· 키워드
오류제보하기
A recent study conducted at the University of Tennessee Medical Center using a large dataset from the National Cancer Database (NCDB) reported the use of nomograms for predicting Oncotype DXTM (ODX) scores with clinicopathologic data. We reviewed the data of 218 patients who underwent the ODX test at a single institution in Korea to confirm that nomograms can accurately predict ODX score groups using our data, which differ from those of the NCDB in terms of ethnicity. The concordance index (c-index) of nomograms was much lower than that of the University of Tennessee Medical Center for high- and low-risk groups of commercial ODX and Trial Assigning Individualized Options for Treatment values. Although the nomogram for predicting ODX scores was based on a large dataset, it could not be generalized to patients in Asia. Further studies using large datasets of patients from different ethnicities should be performed to develop a nomogram applicable to patients worldwide.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Halpern N / 2017 / Oncotype Dx recurrence score among BRCA1/2 germline mutation carriers with hormone receptors positive breast cancer / Int J Cancer 140:2145~2149
2006 / NSABP study confirms Oncotype DX predicts chemotherapy benefit in breast cancer patients / Oncology (Williston Park) 20:789~790
Paik S / 2006 / Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer / J Clin Oncol 24:3726~3734
Sparano JA / 2006 / TAILORx: trial assigning individualized options for treatment (Rx) / Clin Breast Cancer 7:347~350
Gradishar WJ / 2015 / NCCN guidelines insights breast cancer, version 1.2016 / J Natl Compr Canc Netw 13:1475~1485
2006 / NSABP study confirms Oncotype DX predicts chemotherapy benefit in breast cancer patients / Oncology (Williston Park) 20:789~790
Paik S / 2006 / Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer / J Clin Oncol 24:3726~3734
Sparano JA / 2006 / TAILORx: trial assigning individualized options for treatment (Rx) / Clin Breast Cancer 7:347~350
Gradishar WJ / 2015 / NCCN guidelines insights breast cancer, version 1.2016 / J Natl Compr Canc Netw 13:1475~1485
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