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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 1 - 8 (8page)
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Because dopamine (DA) is one of the most critical neurotransmitters that influence a wide variety of motivated human behaviors, it is necessary to develop a facile diagnostic tool that can quantify the physiological level. In this study, core–shell magnetic silica nanoparticles (Fe3O4@SiO2) were prepared using a modified sol–gel reaction. The Fe3O4@SiO2 were functionalized using 3-aminophenylboronic acid (APBA) via a facile and rapid synthetic route, hereafter referred to as Fe3O4@SiO2@APBA The resultant Fe3O4@SiO2@APBA not only adsorbed DA molecules, but also were easily separated from solution using a simple magnetic manipulation. The adsorbed amounts of DA by the Fe3O4@SiO2@APBA were quantified by measuring the changes in fluorescence intensity of polydopamine (at 463 nm) originated from the self-polymerized DA remained in the supernatant before and after the adsorption process. The Fe3O4@SiO2@APBA exhibited two-stage adsorption behavior for DA, and the maximal adsorption capacity was 108.46 μg/g at pH 8.5. Our particle system demonstrated the potential application for extracting compounds with cis-diols (including catechol amines) from the biological fluid.
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참고문헌 (47)
참고문헌 신청
K. C. Berridge / 2009 / Dissecting components of reward: ‘liking’, ‘wanting’, and learning / Curr. Opin. Pharmacol 9:65~73
Y. Bu / 2015 / The characteristic Ag(core)Au(shell)nanoparticles as SERS substrates in detecting dopamine molecules at various pH ranges / Int. J. Nanomed 10:47~54
A. P. Silwal / 2017 / Raman spectroscopic signature markers of dopamine-human dopamine transporter interaction in living cells / ACS Chem. Neurosci 8:1510~1518
Y. J. Kang / 2018 / Therapeutic nanoplatforms and delivery strategies for neurological disorders / Nano Converg 5:35
J. H. An / 2015 / Surface-enhanced Raman spectroscopy detection of dopamine by DNA Targeting amplification assay in Parkisons’s model / Biosens. Bioelectron 67:739~746
Y. Bu / 2015 / The characteristic Ag(core)Au(shell)nanoparticles as SERS substrates in detecting dopamine molecules at various pH ranges / Int. J. Nanomed 10:47~54
A. P. Silwal / 2017 / Raman spectroscopic signature markers of dopamine-human dopamine transporter interaction in living cells / ACS Chem. Neurosci 8:1510~1518
Y. J. Kang / 2018 / Therapeutic nanoplatforms and delivery strategies for neurological disorders / Nano Converg 5:35
J. H. An / 2015 / Surface-enhanced Raman spectroscopy detection of dopamine by DNA Targeting amplification assay in Parkisons’s model / Biosens. Bioelectron 67:739~746
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