지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한창상학회 Journal of Wound Management and Research Journal of Wound Management and Research Vol.16 No.3
- 발행연도
- 2020.1
- 수록면
- 137 - 143 (7page)
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초록· 키워드
오류제보하기
Background: Seromas are caused by leakage of lymphovascular fluid into postoperative dead space. This is the most common complication after reconstructive breast surgery. The purpose of this study is to demonstrate the utility of seroma-preventing substances by using a collagen-enhanced fibrin sealant on a rat mastectomy model.Methods: Thirty-six Sprague-Dawley rats were divided into three groups. After mastectomy and axillary lymph node dissection, normal saline was applied to the dead spaces in group 1 (control). In group 2, a collagen-enhanced fibrin sealant was applied, and in group 3, triamcinolone acetate solution was applied. Afterwards, the amount of seroma was measured by three-dimensional micro-computed tomography (3D micro-CT) volumetry analysis and manual aspiration after 7 and 14 days, respectively.Results: The volume of seroma were significantly reduced in groups 2 and 3 compared to group 1 in both 3D micro-CT volumetry analysis and manual aspiration on postoperative day 7 (P<0.001). In addition, the results observed in day 14 also showed a decrease in the amount of seroma analyzed by CT in groups 2 and 3 compared to group 1 (P<0.05). In histopathologic examination inflammation was observed more frequently in group 1 and angiogenesis was more active in group 2.Conclusion: The use of a collagen-enhanced fibrin sealant (Collaseal) is as effective as triamcinolone control injected in a rat mastectomy model.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Yan WH / 2018 / Natural history of seroma following the immediate latissimus dorsi flap method of breast reconstruction / Chin Med J(Engl) 131:1674~1679
Hart AM / 2017 / A prospective randomized trial of the efficacy of fibrin glue, triamcinolone acetonide, and quilting sutures in seroma prevention after latissimus dorsi breast reconstruction / Plast Reconstr Surg 139:854e~863e
Lee J / 2016 / Effects of quilting suture interval on donor site seromas after breast reconstruction with latissimus dorsi muscle flap: a randomized trial / Clin Breast Cancer 16:e159~e164
Taghizadeh R / 2008 / Triamcinolone reduces seroma re-accumulation in the extended latissimus dorsi donor site / J Plast Reconstr Aesthet Surg 61:636~642
김종성 / 2019 / Use of Abnobaviscum to treat refractory seroma after breast reconstruction with a latissimus dorsi flap: A case report / Archives of Aesthetic Plastic Surgery 25(2):73~78
Hart AM / 2017 / A prospective randomized trial of the efficacy of fibrin glue, triamcinolone acetonide, and quilting sutures in seroma prevention after latissimus dorsi breast reconstruction / Plast Reconstr Surg 139:854e~863e
Lee J / 2016 / Effects of quilting suture interval on donor site seromas after breast reconstruction with latissimus dorsi muscle flap: a randomized trial / Clin Breast Cancer 16:e159~e164
Taghizadeh R / 2008 / Triamcinolone reduces seroma re-accumulation in the extended latissimus dorsi donor site / J Plast Reconstr Aesthet Surg 61:636~642
김종성 / 2019 / Use of Abnobaviscum to treat refractory seroma after breast reconstruction with a latissimus dorsi flap: A case report / Archives of Aesthetic Plastic Surgery 25(2):73~78
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