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논문 기본 정보

자료유형
학술저널
저자정보
Park Ju-sik (Keimyung University Daegu Republic of Korea) Park Jin-han (Daegu Haany University Gyungsan Republic of Korea)
저널정보
J-INSTITUTE Protection Convergence Protection Convergence Vol.4 No.1
발행연도
2019.1
수록면
11 - 18 (8page)

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Singi-Hwan(SH) is a widely used prescription for treating kidney inflammation in Korea. However, the protective effect of SH on maximal exercise performance(MEP) is not well studied. Fatigue is the physiological phenomena after working and exercise to improve physical strength. The purpose of this study was to evaluate the MEP effect of SH using the FST model. To study the protective effect of SH on endurance maximal exercise performance by in vivo experiment. The mouse is largely divided into three groups; Non-swimming group, saline treatment - swimming load test group and SH processing swimming group. The swimming load test group was subdivided into the swimming control group(Control) and the Singi-Hwan supply group(SH). SH was orally administered 2 weeks before FST administration. After FST, immobility time, oxygen consumption was measured by physiological test, and serum was collected for biochemical analysis. Immobility, oxygen consumption and biochemical factors were increased FST - induced MEP. Immobility time was significantly decreased in SH treatment group compared to control group. Oxygen consumption was also significantly decreased by SH treatment. The increase of lactic acid and lactate dehydrogenase after FST was inhibited by SH treatment. Consumption of energy sources(free fatty acid and triglyceride) and energy recovery were improved by SH treatment after FST. In conclusion, SH suppressed the increase of immobility time, oxygen consumption and biochemical factors after FST. All the results suggest SH might be a potentially protective ingredient for the anti-fatigue functional food. In conclusion, SH can be used as a beneficial medium to improve maximal exercise performance and the ability to protect the body from fatigue. This study indicates that SH protects mice from physical fatigue and improves exercise performance. Therefore, it has a potential for the pharmacological effect of anti-fatigue. Our study provides new sight into the protective effects of SH on the fatigue status of mice. Additional studies are needed to find the mechanism of association between each single herb.
#Protection #Singi-Hwan #Maximal Exercise Performance(MEP) #Forced Swimming Test(FST) #Lactic Acid

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참고문헌 (26)

참고문헌 신청
Bassuk SS / 2005 / Epidemiological Evi-dence for the Role of Physical Activity in Re-ducing Risk of Type 2 Diabetes and Cardio-vascular Disease / Journal of Applied Physiology 99:1193~1204 google schola Roberts CK / 2005 / Effects of Exercise and Diet on Chronic Disease / Journal of Ap-plied Physiology 98:3~30 google schola Jenkins RR / 1993 / Exercise, Oxidative Stress, and Antioxidants / International Journal of Sport Nutrition 3:356~375 google schola 현경예 / 2009 / 20대 젊은이들에 있어 1회성 유산소운동 시 염증 표지자와 혈액변인들 간의 상관관계 / 생명과학회지 19(11):1658~1665 dbpia Moxnes JF / 2012 / The Kinetics of Lactate Production and Removal during Whole-body Exercise / Theoretical Biology & Medical Modelling 9:7~19 google schola

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