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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 92 - 98 (7page)
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Heat shock proteins (HSPs) are highly conserved cellular proteins that contribute to adaptive responses of organisms to a variety of stressors. In response to stressors, cellular levels of HSPs are increased and play critical roles in protein stability, folding and molecular trafficking. The mRNA expression pattern of two well-known heat shock protein transcripts, HSP70 and HSP90 were studied in two tissues of nerve ganglia, cerebral ganglion and pleuropedal ganglion of Pacific abalone (Haliotis discus hannai). It was observed that both HSP70 and HSP90 transcripts were upregulated under heat stress in both ganglion tissues. Expression level of HSP70 was found higher than HSP90 in both ganglia whereas cerebral ganglion showed higher expression than pleuropedal ganglion. The HSP70 and HSP90 showed higher expression at Day-1 after exposed to heat stress, later decreased at Day-3 and Day-7 onwards. The present result suggested that HSP70 and HSP90 synthesize in nerve ganglion tissues and may provide efficient protection from stress.
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참고문헌 (37)
참고문헌 신청
Batulan Z / 2006 / Induction of multiple heat shock proteins and neuroprotection in a primary culture model of familial amyotrophic lateral sclerosis / Neurobiol Dis 24:213~225
Bittner GD / 1988 / Long term survival of severed distal axonal stumps in vertebrates and invertebrates / Am Zool 28:1165~1179
Bittner GD / 1991 / Long-term survival of anucleate axons and its implications for nerve regeneration / Trends Neurosci 14:188~193
Bohush A / 2019 / HSP90 and Its Co-Chaperones in Neurodegenerative Diseases / Int J Mol Sci :4976
Breitburg D / 2018 / Declining oxygen in the global ocean and coastal waters / Science :6371
Bittner GD / 1988 / Long term survival of severed distal axonal stumps in vertebrates and invertebrates / Am Zool 28:1165~1179
Bittner GD / 1991 / Long-term survival of anucleate axons and its implications for nerve regeneration / Trends Neurosci 14:188~193
Bohush A / 2019 / HSP90 and Its Co-Chaperones in Neurodegenerative Diseases / Int J Mol Sci :4976
Breitburg D / 2018 / Declining oxygen in the global ocean and coastal waters / Science :6371
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