지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 93 - 102 (10page)
이용수
초록· 키워드
오류제보하기
Scientific and technological advances achieved with industrial expansion have led to an ever-increasing demand for heavy metals. This demand has, in turn, led to increased contamination of soil, water and air with these metals. Chronic exposure to metals may be detrimental not only to occupational workers but also to the nonoccupational population exposed to these metals. Manganese (Mn), a commonly used heavy metal, is an essential cofactor for many enzymatic processes that drive biological functions. However, it is also a potential source of neurotoxicity, particularly in the field of movement disorders. The typical manifestation of Mn overexposure is parkinsonism, which may be difficult to differentiate from the more common idiopathic Parkinson’s disease. In addition to environmental exposure to Mn, other potential etiologies causing hypermanganesemia include systemic health conditions, total parenteral nutrition and genetic mutations causing Mn dyshomeostasis. In this review, we critically analyze Mn and discuss its sources of exposure, pathophysiology and clinical manifestations. We have highlighted the global public health impact of Mn and emphasize that movement disorder specialists should record a detailed social and occupational history to ensure that a toxic etiology is not misdiagnosed as a neurodegenerative disease. In the absence of a definite therapeutic option, early diagnosis and timely institution of preventive measures are the keys to managing its toxic effects.
목차
등록된 정보가 없습니다.
참고문헌 (83)
참고문헌 신청
Jaishankar M / 2014 / Toxicity, mechanism and health effects of some heavy metals / Interdiscip Toxicol 7:60~72
Jan AT / 2015 / Heavy metals and human health : mechanistic insight into toxicity and counter defense system of antioxidants / Int J Mol Sci 16:29592~29630
Engwa GA / 2019 / Poisoning in the modern world: new tricks for an old dog? / IntechOpen :77~99
Mertz W / 1981 / The essential trace elements / Science 213:1332~1338
Chen P / 2016 / Metals and Neurodegeneration / F1000Res 366
Jan AT / 2015 / Heavy metals and human health : mechanistic insight into toxicity and counter defense system of antioxidants / Int J Mol Sci 16:29592~29630
Engwa GA / 2019 / Poisoning in the modern world: new tricks for an old dog? / IntechOpen :77~99
Mertz W / 1981 / The essential trace elements / Science 213:1332~1338
Chen P / 2016 / Metals and Neurodegeneration / F1000Res 366
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Effect of Manganese Content on the Magnetic Susceptibility of Ferrous-Manganese Alloys: Correlation between Microstructure on X-Ray Diffraction and Size of the Low-Intensity Area on MRI
Investigative Magnetic Resonance Imaging
2015 .01
-
임신 여성 근로자의 제대혈 중 망간 농도 추정
한국산업보건학회지
2018 .01
-
A Case-Control Study of Skin Cancer and Exposure of Toxic Heavy Metals
Annals of Dermatology
2018 .01
-
Manganese-enhanced MR imaging of brain activation related to noxious stimuli
한국실험동물학회 학술발표대회 논문집
2015 .08
-
From Neurons to Social Beings: Short Review of the Mirror Neuron System Research and Its Socio-Psychological and Psychiatric Implications
Clinical Psychopharmacology and Neuroscience
2018 .01
-
Concentrations of trace metals in serum: Implications for type 2 diabetes mellitus and gender difference
Environmental Analysis Health and Toxicology
2025 .03
-
Corrosion Behaviors of Dental Implant Alloy after Micro-sized Surface Modification in Electrolytes Containing Mn Ion
Journal of Korean Dental Science
2018 .12
-
Association of Hair Manganese Level with Symptoms in Attention-Deficit/Hyperactivity Disorder
PSYCHIATRY INVESTIGATION
2015 .01
-
Toxicometallomics of Cadmium, Manganese and Arsenic with Special Reference to the Roles of Metal Transporters
Toxicological Research
2019 .10
-
Effect of Chelation Therapy on a Korean Patient With Brain Manganese Deposition Resulting From a Compound Heterozygous Mutation in the SLC39A14 Gene
Journal Of Movement Disorders
2022 .05
-
Effect of Hfe Deficiency on Memory Capacity and Motor Coordination after Manganese Exposure by Drinking Water in Mice
Toxicological Research
2015 .12
-
Expression of Phospholipase A2 Receptor in Pediatric Hepatitis B Virus-Related Membranous Nephropathy
Childhood Kidney Diseases
2020 .01
-
Manganese-based hollow nanoplatforms for MR imaging-guided cancer therapies
생체재료학회지
2022 .09
-
Regional Differences in the Effects of Social Relations on Depression Among Korean Elderly and the Moderating Effect of Living Alone
예방의학회지
2021 .11
-
토양 특성에 따른 중금속이 식물에 미치는 영향 연구
환경독성보건학회 심포지엄 및 학술대회
2019 .10
-
Bioaccumulation and health risk assessment of heavy metals in Musa paradisiaca, Zea mays, Cucumeropsis manii and Manihot esculenta cultivated in Onne, Rivers State, Nigeria
Environmental Analysis Health and Toxicology
2020 .06
-
Evaluation of metal contamination and phytoremediation potential of aquatic macrophytes of East Kolkata Wetlands, India
Environmental Analysis Health and Toxicology
2016 .12
-
Environmental Exposures to heavy Metals and Respiratory Diseases
환경독성보건학회 심포지엄 및 학술대회
2022 .05
-
Loss of Hfe Function Reverses Impaired Recognition Memory Caused by Olfactory Manganese Exposure in Mice
Toxicological Research
2015 .03
-
Blood lead and manganese in association with attention-deficit hyperactivity disorder in school-aged children
환경독성보건학회 심포지엄 및 학술대회
2015 .10
이 논문의 저자 정보
최근 본 자료
댓글(0)
0