지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 101 - 113 (13page)
이용수
초록· 키워드
오류제보하기
Objectives: Bladder storage symptoms including nocturia is the most common cause of sleep disturbance in all age groups. Sleep disturbance is also a main cause of nocturia so that sleep recovery can clinically improve nocturia. Melatonin has main action to induce sleep and additional effects of smooth muscle relaxation, free radical scavenging, anti-inflammation, et cetera. This study was evaluated the improvement of sleep quality after administrating prolonged-release melatonin in elderly patients with overactive bladder and chronic insomnia. Methods: This clinical trial was performed with a randomized single open study. Thirty-seven patients with overactive bladder and chronic insomnia were initially enrolled in this study. After 4 or 12 weeks treating with 2 mg of prolongedrelease melatonin, clinical outcomes were evaluated with OABSS, IPSS, PSQI and WHO 5 well-being index. Results: Of the 37 patients, 34 (91.9%) were included in the ITT group and 26 (76.5%) in the PP group. In the primary outcome of PP group, significant improvements were observed in total OABSS and nocturia frequencies at 12 weeks, respectively. Secondary outcome measurement including in voiding, storage symptoms, and total IPSS scores showed the improvement at 4 and 12 weeks and in total and sleep quality PSQI scores at 12 weeks, and in quality of life scores of the WHO 5 well-being index at 12 weeks. Only one (3.8%) adverse event was observed. Conclusions: These results suggest clearly that prolonged-release melatonin in elderly patients with overactive bladder and chronic insomnia has the potential to control concomitant voiding and sleep difficulty.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
정성진 / 2011 / Korean Version of the Overactive Bladder Symptom Score Questionnaire: Translation and Linguistic Validation / International Neurourology Journal 15(3):135~142
김재헌 / 2013 / Homogeneity Among the Korean International Prostate Symptom Score Questionnaires Used in Real Practice / Investigative and Clinical Urology 54(4):249~251
Mollayeva T / 2016 / The Pittsburgh sleep quality index as a screening tool for sleep dysfunction in clinical and non-clinical samples : A systematic review and meta-analysis / Sleep Med Rev 25:52~73
Moon YS / 2014 / The relationship of the Korean version of the WHO Five Well-Being Index with depressive symptoms and quality of life in the communitydwelling elderly / Asian J Psychiatr 9:26~30
Griebling TL / 2016 / Incidence and Remission of Nocturia : A Systematic Review and MetaAnalysis / J Urol 196:1710~1711
김재헌 / 2013 / Homogeneity Among the Korean International Prostate Symptom Score Questionnaires Used in Real Practice / Investigative and Clinical Urology 54(4):249~251
Mollayeva T / 2016 / The Pittsburgh sleep quality index as a screening tool for sleep dysfunction in clinical and non-clinical samples : A systematic review and meta-analysis / Sleep Med Rev 25:52~73
Moon YS / 2014 / The relationship of the Korean version of the WHO Five Well-Being Index with depressive symptoms and quality of life in the communitydwelling elderly / Asian J Psychiatr 9:26~30
Griebling TL / 2016 / Incidence and Remission of Nocturia : A Systematic Review and MetaAnalysis / J Urol 196:1710~1711
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