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논문 기본 정보

자료유형
학술저널
저자정보
Sung Kwon Kim (Department of Neurosurgery Gyeongsang National University Changwon) 윤홍인 (Department of Radiation Oncology Yonsei Cancer Center Yonsei University College of Medicine Seoul) Wan-Soo Yoon (Department of Neurosurgery Incheon St. Mary's Hospital The Catholic University of Korea) Jin Mo Cho (Department of Neurosurgery International St. Mary’s Hospital Catholic Kwandong University Incheon) Jangsup Moon (Department of Neurology Rare Disease Center Seoul National University Hospital Seoul National Uni) Kyung Hwan Kim (Chungnam National University Hospital) 김세훈 (Department of Pathology Severance Hospital Yonsei University College of Medicine) 김영일 (가톨릭대학교) Young Zoon Kim (Samsung Changwon Hospital) Ho Sung Kim (Chungbuk National University Hospital) 도윤식 (충북대학교) Jae-Sung Park (Department of Neurosurgery Seoul St. Mary’s Hospital College of Medicine The Catholic University) Ji Eun Park (Department of Radiology and Research Institute of Radiology Asan Medical Center University of Ulsa) 서영범 (영남대학교) Kyoung-Su Sung (Department of Neurosurgery Dong-A University) 송진호 (가톨릭대학교) Chan Woo Wee (SMG-SNU Boramae Medical Center) Se-Hoon Lee (Samsung Medical Center) Do Hoon Lim (Samsung Medical Center) Jung Ho Im (CHA Bundang Medical Center) 장종희 (연세대학교) 한명훈 (한양대학교) 홍제범 (Department of Neurosurgery Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine Seou) Kihwan Hwang (Department of Neurosurgery Seoul National University Bundang Hospital Seoul National University Col) 박철기 (서울대학교) 이연수 (가톨릭대학교) 곽호신 (국립암센터) KSNO Guideline Working Group (KSNO Guideline Working Group)
저널정보
대한뇌종양학회 Brain Tumor Research and Treatment Brain Tumor Research and Treatment Vol.8 No.1
발행연도
2020.1
수록면
11 - 19 (9page)

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Background The Guideline Working Group of the Korean Society for Neuro-Oncology (KSNO) conducted a nationwide questionnaire survey for diverse queries faced in the treatment of brain tumors. As part II of the survey, the aim of this study is to evaluate the national patterns of clinical practice for patients with diffuse midline glioma and meningioma. Methods A web-based survey was sent to all members of the KSNO by email. The survey included 4 questions of diffuse midline glioma and 6 questions of meningioma (including 2 case scenarios). All questions were developed by consensus of the Guideline Working Group. Results In the survey about diffuse midline glioma, 76% respondents performed histologic confirmation to identify H3K27M mutation on immunohistochemical staining or sequencing methods. For treatment of diffuse midline glioma, respondents preferred concurrent chemoradiotherapy with temozolomide (TMZ) and adjuvant TMZ (63.8%) than radiotherapy alone (34.0%). In the survey about meningioma, respondents prefer wait-and-see policy for the asymptomatic small meningioma without peritumoral edema. However, a greater number of respondents had chosen surgical resection as the first choice for all large size meningiomas without exception, and small size meningiomas with either peritumoral edema or eloquent location. There was no single opinion with major consensus on long-term follow-up plans for asymptomatic meningioma with observation policy. As many as 68.1% of respondents answered that they would not add any adjuvant therapies for World Health Organization grade II meningiomas if the tumor was totally resected including dura. Conclusion The survey demonstrates the prevailing clinical practice patterns for patients with diffuse midline glioma and meningioma among members of the KSNO. This information provides a point of reference for establishing a practical guideline in the management of diffuse midline glioma and meningioma.

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