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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 67 - 71 (5page)
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초록· 키워드
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Tyrosine kinase inhibitors are widely used as targeted treatments for various malignancies. Sorafenib is an orally active tyrosine kinase inhibitor that blocks the signaling pathways of several growth factors. Its use is approved for various malignancies such as unresectable hepatocellular carcinoma, renal cell carcinoma, and gastrointestinal stromal tumors. Several adverse effects have been reported in the literature; however, cardiotoxicity is rare. We present a case of recurrent coronary vasospasm caused by short-term administration (5 days) of sorafenib. Since it caused refractory ischemia after re-administration, we had no choice but to stop the treatment.
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참고문헌 (15)
참고문헌 신청
Llovet JM / 2008 / Sorafenib in advanced hepatocellular carcinoma / N Engl J Med 359:378~390
Chaar M / 2018 / Mechanisms, monitoring, and management of tyrosine kinase inhibitors-associated cardiovascular toxicities / Onco Targets Ther 11:6227~6237
Escudier B / 2007 / Sorafenib in advanced clear-cell renal-cell carcinoma / N Engl J Med 356:125~134
Bruix J / 2012 / Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma : subanalyses of a phase III trial / J Hepatol 57:821~829
Touyz RM / 2018 / Vascular toxicities with VEGF inhibitor therapies-focus on hypertension and arterial thrombotic events / J Am Soc Hypertens 12:409~425
Chaar M / 2018 / Mechanisms, monitoring, and management of tyrosine kinase inhibitors-associated cardiovascular toxicities / Onco Targets Ther 11:6227~6237
Escudier B / 2007 / Sorafenib in advanced clear-cell renal-cell carcinoma / N Engl J Med 356:125~134
Bruix J / 2012 / Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma : subanalyses of a phase III trial / J Hepatol 57:821~829
Touyz RM / 2018 / Vascular toxicities with VEGF inhibitor therapies-focus on hypertension and arterial thrombotic events / J Am Soc Hypertens 12:409~425
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Effect of autophagy modulation on sorafenib-induced cytotoxicity in hepatocellular carcinoma cells
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2019 .01
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Phosphoinositide 3-kinase inhibitors are effective therapeutic drugs for the treatment of hepatocellular carcinoma?
Clinical and Molecular Hepatology
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Non-receptor tyrosine kinase inhibitors enhances β-cell survival by suppressing the PKCδ signal transduction pathway in streptozotocin-induced β‐cell apoptosis
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Usefulness of sarcopenia in patients with advanced hepatocellular carcinoma undergoing sorafenib treatment
대한외과학회 학술대회 초록집
2019 .10
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방사성요오드 불응성 갑상선암에서 티로신키나아제억제제 투여로 유발된 중증 피로감의 관리
International Journal of Thyroidology
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Optimal sequence of systemic therapy after sorafenib failure in patients with hepatocellular carcinoma
Clinical and Molecular Hepatology
2020 .01
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Metastatic Squamous Cell Carcinoma from Lung Adenocarcinoma after Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy
Journal of Pathology and Translational Medicine
2017 .07
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A case report of advanced hepatocellular carcinoma treated with hepatic arterial infusion chemotherapy and sorafenib combination therapy followed by metastasectomy of lung and muscle metastases
Journal of Liver Cancer
2022 .03
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Tumor lysis syndrome following sorafenib treatment in hepatocellular carcinoma
영남의대학술지
2015 .01
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Mechanisms of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Resistance and Strategies to Overcome Resistance in Lung Adenocarcinoma
Tuberculosis and Respiratory Diseases
2016 .01
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Down-Regulation of TGF-β Expression Sensitizes the Resistance of Hepatocellular Carcinoma Cells to Sorafenib
Yonsei Medical Journal
2017 .01
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CORRIGENDUM: CORRECTION OF TEXT. 진행성 갑상선암 환자에서 발생하는 Tyrosine Kinase Inhibitor의 이상반응
International Journal of Thyroidology
2019 .01
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Real-Life Experience of Sorafenib Treatment for Hepatocellular Carcinoma in Korea: From GIDEON Data
Cancer Research and Treatment
2016 .01
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Long-term outcomes of patients with advanced hepatocellular carcinoma who achieved complete remission after sorafenib therapy
Clinical and Molecular Hepatology
2015 .01
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Nivolumab for Advanced Hepatocellular Carcinoma with Multiple Lung Metastases after Sorafenib Failure
Journal of Liver Cancer
2020 .01
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Effects of the mixed formulation of sorafenib and blue honeysuckle on the pharmacokinetics profiles of sorafenib
대한예방한의학회지
2019 .01
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Systemic therapy for advanced hepatocellular carcinoma: consideration for selecting second-line treatment
Journal of Liver Cancer
2021 .09
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An interim safety analysis of hepatocellular carcinoma patients administrating oral vitamin K with or without sorafenib
Annals of Hepato-Biliary-Pancreatic Surgery
2015 .02
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Infiltrative hepatocellular carcinoma with multiple lung metastasis completely cured using nivolumab: a case report
Journal of Liver Cancer
2021 .09
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