지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한뇌혈관외과학회 Journal of Cerebrovascular and Endovascular Neurosurgery Journal of Cerebrovascular and Endovascular Neurosurgery Vol.22 No.1
- 발행연도
- 2020.1
- 수록면
- 8 - 14 (7page)
이용수
초록· 키워드
오류제보하기
Objective: Mechanical thrombectomy (MT) is now an established treatment for acute ischemic stroke (AIS) with large vessel occlusion (LVO) within 6 hours. Since 2018, MT is also recommended from 6-24 hours after selecting with additional multimodal imaging including perfusion imaging. We sought to investigate patients with significant discrepancy in core infarct between computed tomography (CT) and CT perfusion (CTP). Methods: In this retrospective study, patients with AIS who were evaluated for MT using the RAPID software (IschemaView, Redwood City, CA, USA) from February 2018 to March 2019 were included. Cases with discrepancy between infarct volume on non-contrast CT and core volume (cerebral blood flow <30%) as analyzed by RAPID on CTP were analyzed. Results: In the study period, 635 patients were evaluated for acute stroke symptoms. Non-contrast head CT was performed in 635 patients, and CTP with RAPID software post processing was performed in 134 patients. Among the 134 patients, 8 (5.9%) patients had gross discrepancy in core infarct between CT and CTP, with underestimation of infarct by CTP. Evaluation of these cases shows that the likely reason for this discrepancy is recanalization of a LVO, which then leads to erroneously normal or gross underestimate of the core infarct volume determined from CTP post processing analysis. Conclusions: Recanalization of a LVO can lead to erroneously normal or gross underestimation of the core infarct as determined by post processing software analysis of CTP data. The whole composite of hyperacute CT imaging should be examined while making decisions. This caveat of perfusion imaging interpretation has not been reported previously.
목차
등록된 정보가 없습니다.
참고문헌 (8)
참고문헌 신청
Albers GW / 2018 / Thrombectomy for stroke at 6 to 16hours with selection by perfusion imaging / N Engl J Med 378(8):708~718
Campbell BC / 2011 / Cerebral blood flow is the optimal CT perfusion parameter for assessing infarct core / Stroke 42(12):3435~3440
Christensen S / 2010 / Optimal perfusion thresholds for prediction of tissue destined for infarction in the combined EPITHET and DEFUSE dataset / Stroke 41:e297
Ma H / 2019 / Thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke / N Engl J Med 380(19):1795~1803
Nogueira RG / 2018 / Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct / N Engl J Med 378(1):11~21
Campbell BC / 2011 / Cerebral blood flow is the optimal CT perfusion parameter for assessing infarct core / Stroke 42(12):3435~3440
Christensen S / 2010 / Optimal perfusion thresholds for prediction of tissue destined for infarction in the combined EPITHET and DEFUSE dataset / Stroke 41:e297
Ma H / 2019 / Thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke / N Engl J Med 380(19):1795~1803
Nogueira RG / 2018 / Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct / N Engl J Med 378(1):11~21
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