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논문 기본 정보

자료유형
학술저널
저자정보
Matthieu Grasland (Sorbonne Université GRC 001 GREEN Groupe de Recherche Clinique en Neuro-Urologie AP-HP Hôpital Teno) Nicolas Turmel (Sorbonne Université GRC 001 GREEN Groupe de Recherche Clinique en Neuro-Urologie AP-HP Hôpital Teno) Camille Pouyau (Sorbonne Université GRC 001 GREEN Groupe de Recherche Clinique en Neuro-Urologie AP-HP Hôpital Teno) Camille Leroux (Sorbonne Université GRC 001 GREEN Groupe de Recherche Clinique en Neuro-Urologie AP-HP Hôpital Teno) Audrey Charlanes (Sorbonne Université GRC 001 GREEN Groupe de Recherche Clinique en Neuro-Urologie AP-HP Hôpital Teno) Camille Chesnel (Sorbonne Université GRC 001 GREEN Groupe de Recherche Clinique en Neuro-Urologie AP-HP Hôpital Teno) Frédérique Le Breton (Sorbonne Université GRC 001 GREEN Groupe de Recherche Clinique en Neuro-Urologie AP-HP Hôpital Teno) Samer Sheikh-Ismael (Sorbonne Université GRC 001 GREEN Groupe de Recherche Clinique en Neuro-Urologie AP-HP Hôpital Teno) Gérard Amarenco (Sorbonne Université GRC 001 GREEN Groupe de Recherche Clinique en Neuro-Urologie AP-HP Hôpital Teno) Claire Hentzen (Sorbonne Université GRC 001 GREEN Groupe de Recherche Clinique en Neuro-Urologie AP-HP Hôpital Teno)
저널정보
대한소화관운동학회(현 대한소화기능성질환.운동학회) Journal of Neurogastroenterology and Motility (JNM) Journal of Neurogastroenterology and Motility (JNM) Vol.27 No.1
발행연도
2021.1
수록면
119 - 126 (8page)

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Background/AimsExternal anal sphincter (EAS) plays an important role in fecal and gas voluntary continence. Like every muscle, it can be affected by repeated efforts due to fatigability (physiological response) and/or fatigue (pathological response). No standardized fatiguing protocol and measure method to assess EAS fatigability has existed. The aim is to test a simple, standardized protocol for fatiguing and measuring EAS fatigability and fatigue to understand better the part of EAS fatigability in the pathophysiology of fecal incontinence. MethodsPatients with anorectal disorders evaluated with anorectal manometry were included. They had to perform 10 repetitions of maximum voluntary contraction (MVC) of 20 seconds. Measurement was made with an anorectal manometry catheter and a surface recording electromyography (EMG). The primary outcome was the difference in EMG root mean square between the first and the last MVC. Secondary outcomes were differences in other EMG and manometry parameters between the first and the last MVC. Difficulties and adverse effects were recorded. ResultsNineteen patients underwent the fatiguing protocol. All patients completed the entire protocol and no complications were found. No difficulty was declared by the examiner. A significant decrease in root mean square was found between the first and last MVC (0.01020 ± 0.00834 mV vs 0.00661 ± 0.00587 mV; P = 0.002), in maximum anal pressure area under the curve of continuous recordings of anal pressure and mean and total EMG power (P < 0.05). ConclusionsThis protocol is simple and minimally invasive to measure EAS fatigue and fatigability. We highlighted a fatigue of EAS in many patients with anorectal disorders.

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