메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류
인문학
인문학 일반 역사학 철학 종교학 어문학 기타 인문학
사회과학
사회과학 일반 경영학 관광학 교육학 군사학 문헌정보학 법학 사회학 신문방송학 심리과학 정치외교학 지리학 행정학 경제학 무역학 인류학 기타 사회과학
자연과학
자연과학 일반 물리학 생물학 생활과학 수학·통계학 천문학 지구과학 화학 기타 자연과학
공학
공학 일반 건축공학 기계공학 산업공학 재료·에너지공학 전기전자공학 조선해양공학 화학공학 컴퓨터학 기타공학
의약학
의학 일반 간호학 수의학 약학 한의학 기초의학 임상의학 기타 의약학
농수해양학
농수해양학 일반 농학 수산학 식품과학 임학 축산학 해상운송학 기타 농수해양학
예술체육학
예술 일반 디자인 미술 미용 사진 음악학 의상 체육 공연매체예술 기타 예술체육학
복합학
학제간연구 과학기술학 뇌인지과학 기술정책 기타 복합학

ENG

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Giovanni Di Nardo (NESMOS Department School of Medicine and Psychology Sapienza University of Rome Sant’Andrea Univers) Federica Viscogliosi (Department of Translational Medical Science Section of Pediatrics University of Naples “Federico II) Francesco Esposito (Radiology Unit Santobono-Pausilipon Children’s Hospital Naples Italy) Vincenzo Stanghellini (Department of Medical and Surgical Sciences St. Orsola-Malpighi Hospital University of Bologna Ital) Maria Pia Villa (NESMOS Department School of Medicine and Psychology Sapienza University of Rome Sant’Andrea Univers) Pasquale Parisi (NESMOS Department School of Medicine and Psychology Sapienza University of Rome Sant’Andrea Univers) Alessia Morlando (Department of Translational Medical Science Section of Pediatrics University of Naples “Federico II) Girolamo Calò (Department of Medical Sciences University of Ferrara Ferrara Italy) Roberto De Giorgio (Department of Medical Sciences University of Ferrara Ferrara Italy)
저널정보
대한소화관운동학회(현 대한소화기능성질환.운동학회) Journal of Neurogastroenterology and Motility (JNM) Journal of Neurogastroenterology and Motility (JNM) Vol.25 No.4
발행연도
2019.1
수록면
508 - 514 (7page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
Pediatric chronic intestinal pseudo-obstruction is a rare disorder characterized by a severe impairment of gastrointestinal motility leading to intestinal obstruction symptoms in the absence of mechanical causes. The diagnosis is usually clinical and diagnostic work is usually aimed to rule out mechanical obstruction and to identify any underlying diseases. Treatment is challenging and requires a multidisciplinary effort. In this manuscript we describe the youngest child successfully treated with the orally administrable, long-acting, reversible anti-cholinesterase drug, pyridostigmine. Like other drugs belonging to cholinesterase inhibitors, pyridostigmine enhances gut motility by increasing acetylcholine availability in the enteric nervous system and neuro-muscular junctions. Based on the direct evidence from the reported case, we reviewed the current literature on the use of pyridostigmine in severe pediatric dysmotility focusing on intestinal pseudo-obstruction. The overall data emerged from the few published studies suggest that pyridostigmine is an effective and usually well tolerated therapeutic options for patients with intestinal pseudo-obstruction. More specifically, the main results obtained by pyridostigmine included marked reduction of abdominal distension, reduced need of parenteral nutrition, and improvement of oral feeding. The present case and review on pyridostigmine pave the way for eagerly awaited future randomized controlled studies testing the efficacy of cholinesterase inhibitors in pediatric severe gut dysmotility.
#Cholinesterase inhibitors #Enteric nervous system #Gastrointestinal motility #Intestinal pseudo-obstruction #Pyridostigmine bromide

목차

등록된 정보가 없습니다.

참고문헌 (25)

참고문헌 신청
Di Nardo G / 2016 / Chronic intestinal pseudoobstruction in children and adults: diagnosis and therapeutic options / Neurogastroenterol Motil Crossref Thapar N / 2018 / Paediatric intestinal pseudo-obstruction : evidence and consensus-based recommendations from an ESPGHAN-led expert group / J Pediatr Gastroenterol Nutr 66:991~1019 google schola Law NM / 2001 / Cholinergic stimulation enhances colonic motor activity, transit, and sensation in humans / Am J Physiol Gastrointest Liver Physiol 281:G1228~G1237 google schola Chaudhary NA / 1961 / Human colonic motility: a comparative study of normal subjects, patients with ulcerative colitis, and patients with the irritable colon syndrome. II. The effect of prostigmin / Gastroenterology 40:18~26 google schola Valle RG / 2014 / Neostigmine for acute colonic pseudo-obstruction:a meta-analysis / Ann Med Surg (Lond) 19(3):60~64 google schola

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0