지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.93 No.5
- 발행연도
- 2017.11
- 수록면
- 272 - 276 (5page)
이용수
초록· 키워드
오류제보하기
Purpose: Predicting the need for surgical intervention among patients with intestinal obstruction is challenging. The delta neutrophil index (DNI) has been suggested as a useful marker of immature granulocytes, which indicate an infection or sepsis. In this study, we evaluated the impact of the DNI as an early predictor of operation among patients with intestinal obstruction.
Methods: A total of 171 patients who were diagnosed with postoperative intestinal obstruction were enrolled in this study. Medical records, including data for the initial CRP level, WBC count, and DNI were reviewed. Receiver operating characteristic (ROC) curves were generated to clarify the optimal DNI cutoff values for predicting an operation.
Results: Among the 171 patients, 38 (22.2%) needed surgical intervention. The areas under the initial CRP, WBC, and DNI ROC curves were 0.460, 0.449, and 0.543, respectively. The optimal cutoff value for predicting further surgical intervention according to the initial DNI level was 4.3%. The accuracy of the cutoff value was 74.9%, the sensitivity was 23.7%, and the specificity was 89.5% (positive predictive value, 23.7%; negative predictive value, 89.5%). In the multivariate analysis, initial DNI levels ≥ 4.3% were significantly associated with surgical intervention (odd ratio, 3.092; 95% confidence interval, 1.072–8.918; P = 0.037).
Conclusion: The initial DNI level in patients with intestinal obstruction may be a useful predictor for determining the need for surgical intervention.
Methods: A total of 171 patients who were diagnosed with postoperative intestinal obstruction were enrolled in this study. Medical records, including data for the initial CRP level, WBC count, and DNI were reviewed. Receiver operating characteristic (ROC) curves were generated to clarify the optimal DNI cutoff values for predicting an operation.
Results: Among the 171 patients, 38 (22.2%) needed surgical intervention. The areas under the initial CRP, WBC, and DNI ROC curves were 0.460, 0.449, and 0.543, respectively. The optimal cutoff value for predicting further surgical intervention according to the initial DNI level was 4.3%. The accuracy of the cutoff value was 74.9%, the sensitivity was 23.7%, and the specificity was 89.5% (positive predictive value, 23.7%; negative predictive value, 89.5%). In the multivariate analysis, initial DNI levels ≥ 4.3% were significantly associated with surgical intervention (odd ratio, 3.092; 95% confidence interval, 1.072–8.918; P = 0.037).
Conclusion: The initial DNI level in patients with intestinal obstruction may be a useful predictor for determining the need for surgical intervention.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (23)
참고문헌 신청
[학술지(정기간행물)] - Mucha P Jr. / 1987 / Small intestinal obstruction / Surg Clin North Am 67 : 597 ~ 620
[학술지(정기간행물)] - Bizer LS / 1981 / Small bowel obstruction : the role of nonoperative treatment in simple intestinal obstruction and predictive criteria for strangulation obstruction / Surgery 89 : 407 ~ 413
[학술지(정기간행물)] - Cheadle WG / 1988 / The importance of early diagnosis of small bowel obstruction / Am Surg 54 : 565 ~ 569
[학술지(정기간행물)] - Schein M / 2010 / Small bowel obstruction-who needs an operation? / World J Surg 34 : 920 ~ 922
[학술지(정기간행물)] - Cevikel MH / 2004 / C-reactive protein may be a marker of bacterial translocation in experimental intestinal obstruction / ANZ J Surg 74 : 900 ~ 904
[학술지(정기간행물)] - Bizer LS / 1981 / Small bowel obstruction : the role of nonoperative treatment in simple intestinal obstruction and predictive criteria for strangulation obstruction / Surgery 89 : 407 ~ 413
[학술지(정기간행물)] - Cheadle WG / 1988 / The importance of early diagnosis of small bowel obstruction / Am Surg 54 : 565 ~ 569
[학술지(정기간행물)] - Schein M / 2010 / Small bowel obstruction-who needs an operation? / World J Surg 34 : 920 ~ 922
[학술지(정기간행물)] - Cevikel MH / 2004 / C-reactive protein may be a marker of bacterial translocation in experimental intestinal obstruction / ANZ J Surg 74 : 900 ~ 904
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UCI(KEPA) : I410-ECN-0101-2018-514-001438117