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논문 기본 정보

자료유형
학술저널
저자정보
Prashant Singh (Division of Gastroenterology Beth Israel Deaconess Medical Center Boston USA) Yoonjin Seo (Division of Gastroenterology Beth Israel Deaconess Medical Center Boston USA Background/) Sarah Ballou (Division of Gastroenterology Beth Israel Deaconess Medical Center Boston USA Background/) Andrew Ludwig (Division of Gastroenterology Beth Israel Deaconess Medical Center Boston USA Background/) William Hirsch (Division of Gastroenterology Beth Israel Deaconess Medical Center Boston USA Background/) Vikram Rangan (Division of Gastroenterology Beth Israel Deaconess Medical Center Boston USA Background/) Johanna Iturrino (Division of Gastroenterology Beth Israel Deaconess Medical Center Boston USA Background/) Anthony Lembo (Division of Gastroenterology Beth Israel Deaconess Medical Center Boston USA Background/) Judy W Nee (Division of Gastroenterology Beth Israel Deaconess Medical Center Boston USA Background/)
저널정보
대한소화관운동학회(현 대한소화기능성질환.운동학회) Journal of Neurogastroenterology and Motility (JNM) Journal of Neurogastroenterology and Motility (JNM) Vol.25 No.1
발행연도
2019.1
수록면
129 - 136 (8page)

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Background/Aims: Although symptoms related to the pelvic floor, such as pelvic organ prolapse (POP) and lower urinary tract symptoms (LUTS), are common in patients with chronic constipation (CC), its impact is not clear. Our aims were to investigate the following (1) compare pelvic floor symptom related dysfunction in irritable bowel syndrome with constipation (IBS-C) and functional constipation (FC), and (2) symptom correlation with findings on anorectal manometry (ARM) and balloon expulsion test. Methods: This was a retrospective analysis of patients with CC undergoing ARM. IBS-C and FC were diagnosed by Rome III criteria. Pelvic Floor Distress Inventory (PFDI-20) was used to measure pelvic floor symptom distress. Constipation Severity Scale was used to assess constipation severity. Results: A total of 107 patients underwent ARM (64 FC, 43 IBS-C). The overall PFDI-20 score in IBS-C was higher compared with FC patients (118.0 vs 79.2, P = 0.001). In those with IBS-C, POP, LUTS, and colorectal symptoms subscales were all higher compared with FC patients (P < 0.05 for each). On multivariable regression, IBS-C (P = 0.001) and higher constipation severity (P = 0.001) were both independently associated with higher PFDI scores. ARM parameters and abnormal balloon expulsion test did not correlate with PFDI scores. Conclusions: Compared with FC patients, those with IBS-C have significantly higher distress from pelvic floor specific symptoms including POP and LUTS. Higher abdominal pain among IBS-C patients did not entirely explain these findings. A diagnosis of IBS-C and higher constipation severity correlated with PFDI-20 scores, but dyssynergia did not.

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