지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Objective: This study aimed to investigate the association with the functioning of instrumental-activities of daily living (I-ADL) and future development of Alzheimer’s disease (AD) in persons with mild cognitive impairment (MCI). Methods: A total of 116 patients with MCI, aged 65 years to 91 years (male: 88, female: 91 at first visit), from a large hospital center in Korea, were identified. Those who developed at least two consecutive 1-year follow up were diagnosed according to the DSM-5 criteria. Results: When the same level of Mini Mental State Examination (MMSE) scores was given, it could be seen that the probability of AD transfer was predicted differently due to complex changes in I-ADL scores. Specifically, it was observed that with an MMSE score of approximately 23.9 points, as the I-ADL points increase, the odds of transfer also increase approximately 6.1% (I-ADL low: 8.5 points) to 23.5% (I-ADL high: 31.4), therefore odds of transfer are 17.4% higher than I-ADL low condition. Conclusion: The study suggested that even though cognitive problems were not observed due to high MMSE scores, severe damage to I-ADL could lead to AD. Applications may be limited, but such cases may require careful monitoring at the site.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
홍지혜 / 2008 / 경도인지장애 환자에서 복합-일상활동의 제한 / 신경정신의학 47(4):318~324
Petersen RC / 2004 / Mild cognitive impairment as a diagnostic entity / J Intern Med 256:183~194
Brookmeyer R / 1998 / Projections of Alzheimer’s disease in the United States and the public health impact of delaying disease onset / Am J Public Health 88:1337~1342
Linn RT / 1995 / The ‘preclinical phase’ of probable Alzheimer’s disease. A 13-year prospective study of the Framingham cohort / Arch Neurol 52:485~490
De Lepeleire J / 2004 / The diagnostic value of IADL evaluation in the detection of dementia in general practice / Aging Ment Health 8:52~57
Petersen RC / 2004 / Mild cognitive impairment as a diagnostic entity / J Intern Med 256:183~194
Brookmeyer R / 1998 / Projections of Alzheimer’s disease in the United States and the public health impact of delaying disease onset / Am J Public Health 88:1337~1342
Linn RT / 1995 / The ‘preclinical phase’ of probable Alzheimer’s disease. A 13-year prospective study of the Framingham cohort / Arch Neurol 52:485~490
De Lepeleire J / 2004 / The diagnostic value of IADL evaluation in the detection of dementia in general practice / Aging Ment Health 8:52~57
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