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논문 기본 정보

자료유형
학술저널
저자정보
Jihoon Kim (Samsung Medical Center) Joo Myung Lee (Samsung Medical Center) Seung-Hyuk Choi (Samsung Medical Center) Ki Hong Choi (Samsung Medical Center) Taek Kyu Park (Samsung Medical Center) Sung-Ji Park (Samsung Medical Center) Jeong Hoon Yang (Samsung Medical Center) Young Bin Song (Samsung Medical Center) Joo-Yong Hahn (Samsung Medical Center) Mi Ja Jang (Samsung Medical Center) Bon-Kwon Koo (Seoul National University Hospital) Hyeon-Cheol Gwon (Samsung Medical Center)
저널정보
대한심장학회 Korean Circulation Journal Korean Circulation Journal Vol.50 No.5
발행연도
2020.1
수록면
406 - 417 (12page)

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Background and Objectives: Although percutaneous coronary intervention (PCI) is recommended to improve symptoms in patients with stable ischemic heart disease (SIHD), improvement of exercise performance is controversial. This study aimed to investigate changes in exercise duration after PCI according to functional completeness of revascularization by comparing pre- and post-PCI exercise stress test (EST). Methods: Patients with SIHD were enrolled from a prospective PCI registry, and divided into 2 groups: 1) functional complete revascularization (CR) group had a positive EST before PCI and negative EST after PCI, 2) functional incomplete revascularization (IR) group had positive EST before and after PCI. Primary outcome was change in exercise duration after PCI and secondary outcome was major adverse cardiac events (MACE, a composite of any death, any myocardial infarction, and any ischemia-driven revascularization) at 3 years after PCI. Results: A total of 256 patients (149 for CR group, and 107 for IR group) were eligible for analysis. Before PCI, exercise duration was not significantly different between the functional CR and IR groups (median 540 [interquartile range; IQR, 414, 602] vs. 480 [402, 589] seconds, p=0.091). After PCI, however, the CR group had a significantly higher increment of exercise duration than the IR group (median 62.0 [IQR, 12.0, 141.0] vs. 30.0 [−11.0, 103.5] seconds, p=0.011). The functional CR group also had a significantly lower risk of 3-year MACE (6.2% vs. 26.1%; adjusted hazard ratio, 0.19; 95% confidence interval, 0.09–0.41; p<0.001). Conclusions: Functional CR showed a higher increment of exercise duration than functional IR.

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