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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 454 - 462 (9page)
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Purpose: To investigate the clinical utility of transperineal template-guided saturation prostate biopsy (TPB) for risk stratification after transrectal ultrasound (TRUS)-guided biopsy. Materials and Methods: We retrospectively reviewed 155 patients who underwent TPB after previously negative results on TRUS-guided biopsy (n=58) or who were candidates for active surveillance (n=97) fulfilling the PRIAS criteria between May 2017 and November 2018. The patients' clinicopathologic data were reviewed, and the detection of clinically significant cancer (CSC) and upgrading of Gleason grade were identified. Results: The patients' median age and pre-TPB prostate-specific antigen (PSA) value were 65.0 years and 5.74 ng/mL, respectively. A median of 36 biopsy cores was obtained in each patient, with a median TPB core density of 0.88 cores/cm3. Of the 58 males with a previous negative result on TRUS-guided biopsy, prostate cancer (PCa) was detected in 17 males (29.3%), including 8 with CSC. Of the 97 patient candidates for active surveillance, upgrading of the Gleason grade was identified in 31 males (32.0%), 20 with a Gleason grade of 7 (3+4), 6 with a Gleason grade of 7 (4+3), and 5 with a Gleason grade of 8 (4+4). The overall complication rate was 14.8% (23/155), and there were no Clavien–Dindo grade 3 to 5 complications. Conclusions: TPB helps to stratify the risk of PCa that was previously missed or underdiagnosed by TRUS-guided biopsy. TPB might be used as a diagnostic tool to determine risk classification and to help counsel patients with regard to treatment decisions.
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참고문헌 (28)
참고문헌 신청
Loeb S / 2013 / Systematic review of complications of prostate biopsy / Eur Urol 64:876~892
Song W / 2014 / Incidence and management of extended-spectrum betalactamase and quinolone-resistant Escherichia coli infections after prostate biopsy / Urology 84:1001~1007
Mottet N / 2017 / Part 1 : screening, diagnosis, and local treatment with curative intent / Eur Urol 71:618~629
Hayes JH / 2010 / Active surveillance compared with initial treatment for men with low-risk prostate cancer : a decision analysis / JAMA 304:2373~2380
Klotz L / 2010 / Clinical results of long-term follow-up of a large, active surveillance cohort with localized prostate cancer / J Clin Oncol 28:126~131
Song W / 2014 / Incidence and management of extended-spectrum betalactamase and quinolone-resistant Escherichia coli infections after prostate biopsy / Urology 84:1001~1007
Mottet N / 2017 / Part 1 : screening, diagnosis, and local treatment with curative intent / Eur Urol 71:618~629
Hayes JH / 2010 / Active surveillance compared with initial treatment for men with low-risk prostate cancer : a decision analysis / JAMA 304:2373~2380
Klotz L / 2010 / Clinical results of long-term follow-up of a large, active surveillance cohort with localized prostate cancer / J Clin Oncol 28:126~131
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