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논문 기본 정보

자료유형
학술저널
저자정보
Hajime Haimoto (Haimoto Clinic) Shiho Watanabe (Haimoto Clinic) Keiko Maeda (Aichi Shukutoku University) Takashi Murase (Libra Sasashima Medical Clinic) Kenji Wakai (Nagoya University Graduate School of Medicine)
저널정보
대한당뇨병학회 Diabetes and Metabolism Journal Diabetes and Metabolism Journal Vol.45 No.3
발행연도
2021.1
수록면
390 - 403 (14page)

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Background: We evaluated decreases in glycosylated hemoglobin (HbA1c) achieved by reducing carbohydrate from various sources in type 2 diabetes mellitus patients. Methods: We followed up 138 male and 107 female outpatients on a moderate low-carbohydrate diet without diabetic medication for 6 months. Changes in carbohydrate sources (Δcarbohydrate) were assessed from 3-day dietary records at baseline and 6 months, and associations with changes in HbA1c (ΔHbA1c) were examined with Spearman’s correlation coefficients (rs) and multiple regression analysis. Results: ΔHbA1c was –1.5%±1.6% in men and –0.9%±1.3% in women, while Δtotal carbohydrate was –115.3±103.7 g/day in men and –63.6±71.1 g/day in women. Positive associations with ΔHbA1c were found for Δtotal carbohydrate (rs=0.584), Δcarbohydrate from soft drinks (0.368), confectionery (0.361), rice (0.325), bread (0.221), Chinese soup noodles (0.199) in men, and Δtotal carbohydrate (0.547) and Δcarbohydrate from rice (0.376) and confectionery (0.195) in women. Reducing carbohydrate sources by 50 g achieved decreases in HbA1c of 0.43% for total carbohydrate, 1.33% for soft drinks, 0.88% for confectionery, 0.63% for bread, 0.82% for Chinese soup noodles and 0.34% for rice in men and 0.45% for total carbohydrate, 0.67% for confectionery and 0.34% for rice in women, although mean reductions in carbohydrate from these sources were much smaller than that from rice. Conclusion: Decreases in HbA1c achieved by reducing carbohydrate from soft drinks, confectionery, bread and Chinese soup noodles were 2- to 4-fold greater than that for rice. Our results will enable patients to decrease HbA1c efficiently (UMIN000009866).
#Bread #Candy #Carbonated beverages #Diabetes mellitus #type 2 #Diet #carbohydrate-restricted #Dietary carbohydrates #Glycated hemoglobin A #Oryza

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참고문헌 (28)

참고문헌 신청
Jenkins DJ / 1984 / Glycemic responses to foods : possible differences between insulin-dependent and noninsulin-dependent diabetics / Am J Clin Nutr 40:971~981 google schola Gannon MC / 2006 / Control of blood glucose in type 2diabetes without weight loss by modification of diet composition / Nutr Metab(Lond) 3:16 google schola Crapo PA / 1981 / Comparison of serum glucose, insulin, and glucagon responses to different types of complex carbohydrate in noninsulin-dependent diabetic patients / Am J Clin Nutr 34:184~190 google schola Choo VL / 2018 / Food sources of fructose-containing sugars and glycaemic control: systematic review and meta-analysis of controlled intervention studies / BMJ 363:k4644 google schola Jenkins DJ / 2011 / The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes / Diabetologia 54:271~279 google schola

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