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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 681 - 695 (15page)
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Obesity-associated metabolic illnesses are increasing at an alarming rate in Asian countries. A common feature observed in the Asianpopulation is a higher incidence of abdominal obesity—the “skinny-fat” Asian syndrome. In this review, we critically evaluate the relative roles of genetics and environmental factors on fat distribution in Asian populations. While there is an upward trend in obesityamong most Asian countries, it appears particularly conspicuous in Malaysia. We propose a novel theory, the Malaysian gene-environment multiplier hypothesis, which explains how ancestral variations in feast-and-famine cycles contribute to inherited genetic predispositions that, when acted on by modern-day stressors—most notably, urbanization, westernization, lifestyle changes, dietary transitions, cultural pressures, and stress—contribute to increased visceral adiposity in Asian populations. At present, the major determinants contributing to visceral adiposity in Asians are far from conclusive, but we seek to highlight critical areas for further research.
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참고문헌 (83)
참고문헌 신청
World Health Organization / Obesity and Overweight
Flatt JP / 1995 / Use and storage of carbohydrate and fat / Am J Clin Nutr 61(4 Suppl):952S~9S
Ibrahim MM / 2010 / Subcutaneous and visceral adipose tissue : structural and functional differences / Obes Rev 11:11~18
Wang S / 2015 / A novel quantitative body shape score for detecting association between obesity and hypertension in China / BMC Public Health 15:7
Mongraw-Chaffin M / 2015 / The sex and race specific relationship between anthropometry and body fat composition determined from computed tomography : evidence from the multiethnic study of atherosclerosis / PLoS One 10:e0139559
Flatt JP / 1995 / Use and storage of carbohydrate and fat / Am J Clin Nutr 61(4 Suppl):952S~9S
Ibrahim MM / 2010 / Subcutaneous and visceral adipose tissue : structural and functional differences / Obes Rev 11:11~18
Wang S / 2015 / A novel quantitative body shape score for detecting association between obesity and hypertension in China / BMC Public Health 15:7
Mongraw-Chaffin M / 2015 / The sex and race specific relationship between anthropometry and body fat composition determined from computed tomography : evidence from the multiethnic study of atherosclerosis / PLoS One 10:e0139559
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