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논문 기본 정보

자료유형
학술저널
저자정보
Ma. Karen Celine Calapre Ilagan (The Medical City) Elizabeth Paz-Pacheco (University of the Philippines) Darwin Z. Totesora (The Medical City Pasig Philippines) Lyra Ruth Clemente-Chua (The Medical City Pasig Philippines) Jundelle Romulo K. Jalique (The Medical City Pasig Philippines)
저널정보
대한내분비학회 Endocrinology and Metabolism Endocrinology and Metabolism Vol.34 No.4
발행연도
2019.1
수록면
374 - 381 (8page)

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Background: The modified Ferriman-Gallwey (mFG) score is the gold standard for the clinical evaluation of hirsutism. However,racial variations in terminal hair growth limit this tool. This study aimed to determine the mFG cut-off score among Filipino womenand its association with biochemical hyperandrogenism. Methods: A total of 128 Filipino women were included in this prospective cross-sectional study and were divided into two groups: apolycystic ovary syndrome (PCOS) group (n=28) and a non-PCOS group (n=100). The participants underwent mFG score determination, ovarian ultrasound conducted by a single sonographer, and hormone testing. The mFG cut-off score was determined basedon the 95th percentile of the non-PCOS group. Logistic regression was used to analyze the relationship between mFG score and biochemical hyperandrogenism. Results: Although the mFG score was generally low in both the PCOS and non-PCOS groups, the former exhibited a higher meanscore than the latter (4.3±3.0 vs. 2.0±2.2, P<0.001). Normal values for the total mFG score ranged from 0 to 7. Using a cut-offscore of 7, a higher proportion of hirsute women (mFG score ≥7) was observed in the PCOS group versus the non-PCOS group(17.9% vs. 5.0%, P=0.025). Elevated calculated free testosterone (FT) was also found to be significantly associated with hirsutism(odds ratio, 6.2; 95% confidence interval, 1.2 to 32.4 pmol/L; P=0.030). Conclusion: A score of 7 and above constitutes hirsutism in this population of Filipino women. Hirsute women are more likely thannon-hirsute women to have elevated calculated FT.

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