지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 1,339 - 1,346 (8page)
이용수
초록· 키워드
오류제보하기
Background Acinetobacter baumannii is a major opportunistic pathogen causing nosocomial infections. Acinetobacter baumanniipossesses a quorum sensing system consisting of abaI, encoding an autoinducer synthase, and abaR, encoding aputative LuxR type regulator. AbaI is required for motility and biofilm formation in A. baumannii. However, the functionsof AbaR on the expression of abaI, motility, and the formation of biofilm and pellicle have not yet been explored. Objective The aim of this study was to investigate the effects of abaR mutation on the expression of abaI, motility, and theformation of biofilm and pellicle. Methods Functions of AbaR were assessed by the construction of an isogenic mutant and by evaluating the effects of abaRmutation on the expression of abaI, motility, and the formation of biofilm and pellicle. Results The abaR mutant revealed a significant decrease in the expression of abaI. The disruption of abaR resulted in substantialdefects in motility and the formation of biofilm and pellicle. Introduction of abaR in trans complemented the defects. Conclusions AbaR of A. baumannii is required for the expression of abaI and plays important roles in motility and the formationof biofilm and pellicle. AbaR may be considered to be a target of anti-biofilm agents.
목차
등록된 정보가 없습니다.
참고문헌 (3)
참고문헌 신청
Stacy DM / 2012 / Attenuation of quorum sensing in the pathogen Acinetobacter baumannii using non-native N-acyl homoserine lactones / ACS Chem Biol 7:1719~1728
Tomaras AP / 2003 / Attachment to and biofilm formation on abiotic surfaces by Acinetobacter baumannii : involvement of a novel chaperone-usher pili assembly system / Microbiology 149:3473~3484
Tucker AT / 2014 / Defining gene–phenotype relationships in Acinetobacter baumannii through one-step chromosomal gene inactivation / mBio 5:e01313~e01314
Tomaras AP / 2003 / Attachment to and biofilm formation on abiotic surfaces by Acinetobacter baumannii : involvement of a novel chaperone-usher pili assembly system / Microbiology 149:3473~3484
Tucker AT / 2014 / Defining gene–phenotype relationships in Acinetobacter baumannii through one-step chromosomal gene inactivation / mBio 5:e01313~e01314
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
The Effect of Rsd, the Anti-sigma Factor of σ70, on Biofilm Formation and Motility in Escherichia coli
한국미생물학회 학술대회논문집
2016 .04
-
Importance of Motility and Hydrophobicity of Bacterial Cells during the Formation of Early Biofilm in a Simulated Drinking Water Biofilm Reactor
한국미생물학회 학술대회논문집
2015 .04
-
Enhanced Antimicrobial and Anti-biofilm Effect of CM205 Peptide and Its Analogs against Acinetobacter baumannii
한국미생물학회 학술대회논문집
2022 .10
-
Pseudomonas aeruginosa Biofilm, a Programmed Bacterial Life for Fitness
Journal of Microbiology and Biotechnology
2017 .06
-
Molecular Characterization and Antimicrobial Susceptibility of Biofilm-forming Acinetobacter baumannii Clinical Isolates from Daejeon, Korea
대한임상검사과학회지
2018 .01
-
Impact of the Isolation Source on the Biofilm Formation Characteristics of Bacillus cereus
Journal of Microbiology and Biotechnology
2018 .01
-
ppGpp Signaling Plays Critical Role in Biofilm Formation and Virulence of Acinetobacter baumannii
한국미생물학회 학술대회논문집
2020 .10
-
Temperature and Bacterial Biofilm Formation
한국미생물학회 학술대회논문집
2020 .10
-
Effects of Exogenous N-Acyl-Homoserine Lactones on Biofilm Formation and Motility in Acinetobacter nosocomialis
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2020 .06
-
Multispecies Interactions in Biofilms and Implications to Safety of Drinking Water Distribution System
한국미생물·생명공학회지
2019 .01
-
Biofilm Signaling, Composition and Regulation in Burkholderia pseudomallei
Journal of Microbiology and Biotechnology
2023 .01
-
Development of biofilm on the fractured rock under oligotrophic environment : a experimental study using in-situ reactor
대한지질학회 학술대회
2021 .10
-
생물막 모델 시스템
미생물학회지
2016 .06
-
Comparison of the Virulence-Associated Phenotypes of Five Species of Acinetobacter baumannii Complex
Journal of Microbiology and Biotechnology
2016 .01
-
Antibacterial Effect of Chitosan-Modified Fe 3 O 4 Nanozymes on Acinetobacter baumannii
Journal of Microbiology and Biotechnology
2022 .02
-
Epifluorescence Microscopy with Image Analysis as a Promising Method for Multispecies Biofilm Quantification
Journal of Microbiology and Biotechnology
2023 .03
-
Screening of Anti-Biofilm Compounds from Marine-Derived Fungi and the Effects of Secalonic Acid D on Staphylococcus aureus Biofilm
Journal of Microbiology and Biotechnology
2017 .06
-
Disruption of Established Bacterial and Fungal Biofilms by a Blend of Enzymes and Botanical Extracts
Journal of Microbiology and Biotechnology
2023 .06
-
The Influence of Urinary Catheter Materials on Forming Biofilms of Microorganisms
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2017 .03
이 논문의 저자 정보
최근 본 자료
댓글(0)
0