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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 255 - 260 (6page)
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초록· 키워드
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To improve biological effectiveness of bone regeneration, many materials have been used as a bioabsorbable membrane. In this study, bone graft materials (BGM)-loaded glycol chitosan-gellan gum membrane (BGM-GC/GEL) was constructed and compared with a collagen membrane, which is widely used. The film thickness of the BGM-GC/GEL membrane was 0.04~0.05 mm and the commercial Bio-gide of collagen composition was 0.03 mm. In scanning electron microscopy (SEM), it was observed that BGM particles were well dispersed in the GC/GEL membrane. It was evaluated through thermogravimetry analysis (TGA) that the amount of BGM contained in the GC/GEL membrane was 40% (w/w) of the total membrane. Alkaline phosphatase (ALP) analysis shows that ALP values in osteoblasts treated with BGM-GC/GEL membrane tended to increase over time. In cell cytotoxicity tests, both GC/GEL and BGM-GC/GEL membranes showed high cell viability of more than 90% even at 0.1% (w/v) concentration. Therefore, the BGM-GC/GEL membrane can be a good candidate as a guided bone regeneration.
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참고문헌 (14)
참고문헌 신청
Selvig, K. A / 1992 / Regenerative surgery of intrabony periodontal defects using ePTFE barrier membranes: scanningelectronmicroscopic evaluation of retrieved membranes vs. clinical healing / J. Periodontol 63:974~978
Tempro, P. J. / 1993 / Colonization of retrieved polytetrafluoroethylene membranes: morphological and micro-biological observations / J. Periodontol 64:162~168
Zisch, A. H / 2004 / Engineered fibrin matrices for functional display of cell membrane-bound growth factor-like activities: Study of angiogenic signaling by ephrin-B2 / Biomaterials 25:3245~3257
장진운 / 2018 / 골유도재생을 위한 젤란검과 글리콜 키토산 조성 흡수성 차폐막의 평가 / 폴리머 42(5):874~881
Frohbergh, M. E / 2012 / Electrospun hydroxyapatite-containing chitosan nanofibers crosslinked with genipin for bone tissue engineering / Biomaterials 33:9167~9178
Tempro, P. J. / 1993 / Colonization of retrieved polytetrafluoroethylene membranes: morphological and micro-biological observations / J. Periodontol 64:162~168
Zisch, A. H / 2004 / Engineered fibrin matrices for functional display of cell membrane-bound growth factor-like activities: Study of angiogenic signaling by ephrin-B2 / Biomaterials 25:3245~3257
장진운 / 2018 / 골유도재생을 위한 젤란검과 글리콜 키토산 조성 흡수성 차폐막의 평가 / 폴리머 42(5):874~881
Frohbergh, M. E / 2012 / Electrospun hydroxyapatite-containing chitosan nanofibers crosslinked with genipin for bone tissue engineering / Biomaterials 33:9167~9178
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