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논문 기본 정보

자료유형
학술저널
저자정보
Akira Minematsu (Department of Physical Therapy Faculty of Health Science Kio University Japan) Yasue Nishii (Department of Physical Therapy Faculty of Health Science Kio University Japan) Hidetaka Imagita (Department of Physical Therapy Faculty of Health Science Kio University) Susumu Sakata (Department of Physiology Nara Medical University 840 Shijo-cho Kashihara Nara 634-8521 Japan)
저널정보
대한골다공증학회 Osteoporosis and Sarcopenia Osteoporosis and Sarcopenia Vol.5 No.3
발행연도
2019.1
수록면
69 - 74 (6page)

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Objectives: To examine the effects of whole body vibration (WBV) on bone properties in growing rats, and to explore the optimal conditions for enhancing bone properties. Methods: Thirty-six 4-week-old male rats were divided into 1 control and 5 experimental groups. Each experimental group underwent WBV at 15, 30, 45, 60, and 90 Hz (0.5 g, 15 min/d, 5 d/wk) for 8 weeks.We measured bone size, muscle weight and bone mechanical strength of the right tibia. Trabecular bone mass and trabecular bone microstructure (TBMS) of the left tibia were analyzed by micro-computed tomography. Serum levels of bone formation/resorption markers were also measured. Results: WBV at 45 Hz and 60 Hz tended to enhance trabecular bone mass and TBMS parameters. However, there was no difference in maximum load of tibias among all groups. Serum levels of bone resorption marker were significantly higher in the 45-Hz WBV group than in the control group. Conclusions: WBV at 45e60 Hz may offer a potent modality for increasing bone mass during the period of rapid growth. Further studies are needed to explore the optimal WBV conditions for increasing peak bone mass and TBMS parameters. WBV modality may be a potent strategy for primary prevention against osteoporosis.

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