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논문 기본 정보

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학술저널
저자정보
Hyun-Hwa Cha (Department of Obstetrics and Gynecology Kyungpook National University Hospital School of Medicine K) Jong Mi Kim (Department of Obstetrics and Gynecology Kyungpook National University Hospital School of Medicine K) Hyun Mi Kim (Department of Obstetrics and Gynecology Kyungpook National University Hospital School of Medicine K) Mi Ju Kim (Department of Obstetrics and Gynecology Kyungpook National University Hospital School of Medicine K) Gun Oh Chong (Department of Obstetrics and Gynecology Kyungpook National University Hospital School of Medicine K) Won Joon Seong (Department of Obstetrics and Gynecology Kyungpook National University Hospital School of Medicine K)
저널정보
영남대학교 의과대학 Journal of Yeungnam Medical Science Yeungnam University Journal of Medicine 제38권 제1호
발행연도
2021.1
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34 - 38 (5page)

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Background: We aimed to determine whether routine second trimester complete blood cell (CBC) count parameters, including neutrophil-lymphocyte ratio (NLR), lymphocyte-monocyte ratio (LMR), and platelet-lymphocyte ratio (PLR), could predict obstetric outcomes. Methods: We included singleton pregnancies for which the 50-g oral glucose tolerance test and CBC were routinely performed between 24 and 28 weeks of gestation in our outpatient clinic from January 2015 to December 2017. The subjects were divided into three groups according to their pregnancy outcomes as follows: group 1, spontaneous preterm births, including preterm labor and preterm premature rupture of membranes; group 2, indicated preterm birth due to maternal, fetal, or placental causes (hypertensive disorder, fetal growth restriction, or placental abruption); and group 3, term deliveries, regardless of the indication of delivery. We compared the CBC parameters using a bivariate correlation test. Results: The study included 356 pregnancies. Twenty-eight subjects were in group 1, 20 in group 2, and 308 in group 3. There were no significant differences between the three groups in neutrophil, monocyte, lymphocyte, and platelet counts. Although there was no significant difference in NLR, LMR, and PLR between the three groups, LMR showed a negative correlation with gestational age at delivery (r=?0.126, p=0.016). Conclusion: We found that a higher LMR in the second trimester was associated with decreased gestational age at delivery. CBC parameters in the second trimester of pregnancy could be used to predict adverse obstetric outcomes.
#Blood cell count #Lymphocyte-monocyte ratio #Neutrophil-lymphocyte ratio #Preterm

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참고문헌 (22)

참고문헌 신청
Eo WK / 2018 / Diagnostic accuracy of inflammatory markers for distinguishing malignant and benign ovarian masses / J Cancer 9:1165~1172 google schola Kemal Y / 2014 / Elevated serum neutrophil to lymphocyte and platelet to lymphocyte ratios could be useful in lung cancer diagnosis / Asian Pac J Cancer Prev 15:2651~2654 google schola Prodromidou A / 2017 / The diagnostic efficacy of platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio in ovarian cancer / Inflamm Res 66:467~475 google schola Lian L / 2015 / Application of platelet/lymphocyte and neutrophil/lymphocyte ratios in early diagnosis and prognostic prediction in patients with resectable gastric cancer / Cancer Biomark 15:899~907 google schola Temur I / 2018 / Prognostic value of pre-operative neutrophil/lymphocyte ratio, monocyte count, mean platelet volume, and platelet/lymphocyte ratio in endometrial cancer / Eur J Obstet Gynecol Reprod Biol 226:25~29 google schola

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