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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 155 - 164 (10page)
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초록· 키워드
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Background and Objectives: This study was planned to investigate the relationship between iodine intake andthyroid peroxidase antibody in Korean population. Materials and Methods: We used the data of the 6th KoreaNational Health and Nutrition Examination Survey from 2013 to 2015. A total of 6564 subjects who had thedata of thyroid function test were included. We analyzed urinary iodine concentration and thyroid peroxidaseantibody using the complex sample method. Univariate and multivariate analysis were performed according toclinical factors and thyroid function tests. Results: In the multivariate analysis, the thyroid peroxidase antibodypositivity was not related to urinary iodine concentration in the total group (p=0.102), male group (p=0.245)and female group (p=0.098). The urinary iodine concentration was associated with thyroid stimulating hormone(TSH) (p=0.001) and free T4 (p=0.001) but not associated with thyroid peroxidase antibody (p=0.218). Whenhigh TSH group was divided into the positive and negative thyroid peroxidase antibody, high TSH group withnegative thyroid peroxidase antibody increased according to increasing urinary iodine concentration (p＜0.001). But there was no difference in the high TSH group with positive thyroid peroxidase antibody (p=0.826). Conclusion: This study did not show a statistically significant relationship between urinary iodine concentrationand thyroid peroxidase antibody. As urinary iodine concentration increased, thyroid function was decreased onlyin the negative thyroid peroxidase antibody group. This confirmed that the increased urinary iodine concentrationcaused hypothyroidism which was not associated with thyroid peroxidase antibody.
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참고문헌 (24)
참고문헌 신청
Iodine Global Network / Global scorecard of iodine nutrition in 2020
Farebrother J / 2019 / Excess iodine intake : sources, assessment, and effects on thyroid function / Ann N Y Acad Sci 1446(1):44~65
Dong YH / 2014 / Autoimmune thyroid disease : mechanism, genetics and current knowledge / Eur Rev Med Pharmacol Sci 18(23):3611~3618
Kweon S / 2014 / Data resource profile : the Korea National Health and Nutrition Examination Survey(KNHANES) / Int J Epidemiol 43(1):69~77
김원구 / 2017 / Thyroid Stimulating Hormone Reference Range and Prevalence of Thyroid Dysfunction in the Korean Population: Korea National Health and Nutrition Examination Survey 2013 to 2015 / Endocrinology and Metabolism 32(1):106~114
Farebrother J / 2019 / Excess iodine intake : sources, assessment, and effects on thyroid function / Ann N Y Acad Sci 1446(1):44~65
Dong YH / 2014 / Autoimmune thyroid disease : mechanism, genetics and current knowledge / Eur Rev Med Pharmacol Sci 18(23):3611~3618
Kweon S / 2014 / Data resource profile : the Korea National Health and Nutrition Examination Survey(KNHANES) / Int J Epidemiol 43(1):69~77
김원구 / 2017 / Thyroid Stimulating Hormone Reference Range and Prevalence of Thyroid Dysfunction in the Korean Population: Korea National Health and Nutrition Examination Survey 2013 to 2015 / Endocrinology and Metabolism 32(1):106~114
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