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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 소화기인터벤션의학회 International Journal of Gastrointestinal Intervention International Journal of Gastrointestinal Intervention 제9권 제3호
- 발행연도
- 2020.1
- 수록면
- 106 - 110 (5page)
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초록· 키워드
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Background: Recent developments in the design of needle tips used for fine needle biopsy via endoscopic ultrasound (EUS) allows for the procurement of core tissue for histological assessment in addition to cytology. Core tissue provides tissue architecture as well as the ability to perform molecular profiling investigations. We present a single centre study of experience with a new EUS needle with a Franseen tip (AcquireTM; Boston Scientific, Natick, MA, USA). The aim of the study was to assess the diagnostic yield of biopsies from solid lesions throughout the gastrointestinal tract. Methods: We performed a retrospective study of consecutive patients undergoing EUS biopsy between January 2017 and November 2018. Cystic lesions with no solid component were excluded or if samples were not sent for both cytology and histology. Rapid onsite evaluation (ROSE) was performed and the core tissue obtained was sent for histology. Results: Forty-six patients underwent EUS biopsy of solid lesions with specimens sent for both cytology and histology. Lesions included solid pancreatic masses (n = 31), lymph node (n = 3), gastric subepithelial lesion (n = 3), other (n = 9). The mean number of passes per lesion was 1.9 (range 1?4). In 43/46 (93%) of cases, a core specimen was obtained. Tissue obtained by EUS biopsy was adequate for evaluation by ROSE in 39/46 cases (85%). Histological diagnosis was confirmed in 41/46 (89%) cases compared to 31/46 (67%) cases with cytology (P = 0.011). Subgroup analysis of pancreatic lesions showed histological diagnosis was superior to cytology (90% vs 61%, P = 0.007). There were no adverse events. Conclusion: Histological analysis of specimens obtained via EUS biopsy was superior to cytology, particularly in assessment of solid pancreatic lesions.
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참고문헌 (20)
참고문헌 신청
Kim EJ / 2014 / Pilot clinical trial of hedgehog pathway inhibitor GDC-0449(vismodegib)in combination with gemcitabine in patients with metastatic pancreatic adenocarcinoma / Clin Cancer Res 20:5937~5945
Varadarajulu S / 2014 / The changing paradigm in EUS-guided tissue acquisition / Gastrointest Endosc Clin N Am 24:1~7
Kaffes AJ / 2012 / A prospective multicenter evaluation of a new side-port endoscopic ultrasound-fine-needle aspiration in solid upper gastrointestinal lesions / Dig Endosc 24:448~451
Fuccio L / 2014 / Endoscopic ultrasound-guided fine needle aspiration: How to obtain a core biopsy? / Endosc Ultrasound 3:71~81
Al-Haddad M / 2017 / Su1320 prospective assessment of the performance of a new fine needle biopsy device at 2 large referral centers / Gastrointest Endosc 85(Suppl):AB333
Varadarajulu S / 2014 / The changing paradigm in EUS-guided tissue acquisition / Gastrointest Endosc Clin N Am 24:1~7
Kaffes AJ / 2012 / A prospective multicenter evaluation of a new side-port endoscopic ultrasound-fine-needle aspiration in solid upper gastrointestinal lesions / Dig Endosc 24:448~451
Fuccio L / 2014 / Endoscopic ultrasound-guided fine needle aspiration: How to obtain a core biopsy? / Endosc Ultrasound 3:71~81
Al-Haddad M / 2017 / Su1320 prospective assessment of the performance of a new fine needle biopsy device at 2 large referral centers / Gastrointest Endosc 85(Suppl):AB333
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