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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제49권 제1호
- 발행연도
- 2015.1
- 수록면
- 52 - 60 (9page)
이용수
초록· 키워드
오류제보하기
Background: Endoscopic ultrasound–guided fine needle aspiration cytology (EUS-FNAC) is currently the most commonly used procedure for obtaining cytologic specimens of the pancreas. It is accurate, minimally invasive, safe and cost-effective. However, there is discrepancy between cytological and surgical diagnoses. This study was aimed at evaluating the diagnostic accuracy of EUS-FNAC of the pancreas. Methods: We performed a retrospective review of 191 cases of pancreatic lesions initially diagnosed by EUS-FNAC with subsequent histological diagnosis between 2010 and 2012 in the Department of Pathology, Seoul National University Hospital. Cytologic and surgical diagnoses were categorized into five groups: negative, benign, atypical, malignant, and insufficient for diagnosis. Subsequently, 167 cases with satisfactory yield in both surgical and cytology specimens were statistically analyzed to determine correlations with diagnosis. Results: In comparison to surgical diagnoses, cytologic diagnoses were true-positive in 103 cases (61.7%), true-negative in 28 cases (16.8%), false-positive in 9 cases (5.4%), and false-negative in 27 cases (16.1%). The diagnostic accuracy was 78.4%, sensitivity was 79.2%, and specificity was 75.7%. The positive predictive value was 92.0%, and negative predictive value was 50.9%. Conclusions: EUS-FNAC has high accuracy, sensitivity, specificity and positive predictive value. Overcoming the limitations of EUS-FNAC will make it a useful and reliable diagnostic tool for accurate evaluation of pancreatic lesions.
목차
등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
Abraham SC / 2003 / Eosinophilic pancreatitis and increased eosinophils in the pancreas / Am J Surg Pathol 27 : 334 ~ 342
Ardengh JC / 2007 / Diagnosis of pancreatic tumors by endoscopic ultrasound-guided fine-needle aspiration / World J Gastroenterol 13 : 3112 ~ 3116
Bluen BE / 2012 / Accuracy and quality assessment of EUS-FNA : a single-center large cohort of biopsies / Diagn Ther Endosc 2012 : 139563 ~
Erickson RA / 2000 / Factors predicting the number of EUS-guided fine-needle passes for diagnosis of pancreatic malignancies / Gastrointest Endosc 51 : 184 ~ 190
Fisher L / 2009 / Endoscopic ultrasound guided fine needle aspiration of solid pancreatic lesions : performance and outcomes / J Gastroenterol Hepatol 24 : 90 ~ 96
Ardengh JC / 2007 / Diagnosis of pancreatic tumors by endoscopic ultrasound-guided fine-needle aspiration / World J Gastroenterol 13 : 3112 ~ 3116
Bluen BE / 2012 / Accuracy and quality assessment of EUS-FNA : a single-center large cohort of biopsies / Diagn Ther Endosc 2012 : 139563 ~
Erickson RA / 2000 / Factors predicting the number of EUS-guided fine-needle passes for diagnosis of pancreatic malignancies / Gastrointest Endosc 51 : 184 ~ 190
Fisher L / 2009 / Endoscopic ultrasound guided fine needle aspiration of solid pancreatic lesions : performance and outcomes / J Gastroenterol Hepatol 24 : 90 ~ 96
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