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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 767 - 775 (9page)
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Purpose: We aimed to investigate the effect of metal ions from oral prostheses (OPs) released into the saliva of patients with orallichenoid lesions (OLLs). Materials and Methods: Subjects (n=183) were divided into four groups according to the presence or absence of OLL and OP. Concentrations of the metal ions titanium, chromium (Cr), cobalt (Co), nickel (Ni), palladium (Pd), silver (Ag), platinum (Pt),gold (Au), and zirconium (Zr) were measured using a laser-ablation microprobe inductively coupled to a plasma mass spectrometer. Saliva levels of interleukin (IL)-6, IL-1β, IL-8, and tumor necrosis factor-α were detected using an enzyme-linked immunosorbentassay. The reticulation/keratosis, erythema, and ulceration (REU) scoring system was used to assess the severity of OLL. Results: Mean concentrations of IL-6 and IL-8 were statistically higher in OLL patients with OPs. The concentration of Ni washigh in OLL groups. The concentrations of Cr, Ni, and Au ions in the saliva were positively correlated with IL-8. REU scores werepositively correlated with salivary concentrations of IL-6 and IL-8, as well as with concentrations of Cr, Ni, and Au. Conclusion: Increased concentrations of metal ions, especially Ni, in saliva were positively correlated with IL-8 and showed positivecorrelations with the severity of OLL.
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