지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 417 - 423 (7page)
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초록· 키워드
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Purpose: Early recognition and therapeutic intervention are important in patients at high risk of acute respiratory distress syndrome(ARDS). The lung injury prediction score (LIPS) has been used to predict ARDS development; however, it was developedbased on the previous definition of ARDS. We investigated the predictive role of LIPS in ARDS development according to its Berlindefinition in the Korean population. Materials and Methods: This was a retrospective study that enrolled adult patients admitted to the intensive care unit (ICU) at asingle university-affiliated hospital in Korea from September 1, 2018, to August 31, 2019. LIPS at the time of ICU admission andthe development of ARDS were evaluated. Results: Of the 548 enrolled patients, 33 (6.0%) fulfilled the Berlin ARDS definition. The LIPS for non-ARDS and ARDS groupswere 4.96±3.05 and 8.53±2.45, respectively (p<0.001); it was significantly associated with ARDS development (odds ratio 1.48, 95%confidence interval, 1.29?1.69; p<0.001). LIPS >6 predicted the development of ARDS with a sensitivity of 84.8% and a specificityof 67.2% [area under the curve (AUC)=0.82]. A modified LIPS model adjusted for age and severity at ICU admission predicted ICUmortality in patients with ARDS (AUC=0.80), but not in those without ARDS (AUC=0.54). Conclusion: LIPS predicted the development of ARDS as diagnosed by the Berlin definition in the Korean population. LIPS providesuseful information for managing patients with ARDS.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Ashbaugh DG / 1967 / Acute respiratory distress in adults / Lancet 2:319~323
Bernard GR / 1994 / Report of the American-European consensus conference on ARDS: definitions, mechanisms, relevant outcomes and clinical trial coordination / Intensive Care Med 20:225~232
ARDS Definition Task Force / 2012 / Acute respiratory distress syndrome : the Berlin Definition / JAMA 307:2526~2533
Bellani G / 2016 / Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50countries / JAMA 315:788~800
Acute Respiratory Distress Syndrome Network / 2000 / Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome / N Engl J Med 342:1301~1308
Bernard GR / 1994 / Report of the American-European consensus conference on ARDS: definitions, mechanisms, relevant outcomes and clinical trial coordination / Intensive Care Med 20:225~232
ARDS Definition Task Force / 2012 / Acute respiratory distress syndrome : the Berlin Definition / JAMA 307:2526~2533
Bellani G / 2016 / Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50countries / JAMA 315:788~800
Acute Respiratory Distress Syndrome Network / 2000 / Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome / N Engl J Med 342:1301~1308
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