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학술저널
저자정보
김종원 (강남세브란스병원) 안현규 (강남세브란스병원) 고종철 (강남세브란스병원 비뇨기과) 이동구 (강남세브란스병원 비뇨기과) 하지수 (강남세브란스병원) 김재환 (한미제약) 박소정 (한미제약) 조강수 (연세대학교)
저널정보
대한배뇨장애요실금학회 International Neurourology Journal International Neurourology Journal 제24권 제3호
발행연도
2020.1
수록면
278 - 285 (8page)

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Purpose: Overactive bladder (OAB) symptoms might be affected by weather, but only a few clinical studies have investigated this issue. We investigated seasonal variations in OAB-drug prescription rate (DPR) in men using nationwide claims data in Korea. Methods: A total of 2,824,140 men aged over 18 years were included from the Health Insurance Review and Assessment service ? National Patient Sample data between 2012 and 2016. Depending on the monthly average temperature, the seasons were divided into 3 groups, namely, hot (June, July, August, and September), intermediate (April, May, October, and November), and cold (January, February, March, and December) seasons. OAB-DPR was estimated using the claims data, and differences in its rate were examined among the 3 seasonal groups. Results: The overall OAB-DPR was 1.97% (55,574 of 2,824,140). The OAB-DPR were 0.38%, 0.63%, 0.92%, 1.74%, 4.18%, 7.55%, and 9.69% in the age groups of under 30, 30s, 40s, 50s, 60s, 70s, and over 80 years, respectively; thus, the prescription rate increased with age (P<0.001), with a steeper increase after 60 years of age. OAB-DPR was 1.02% in the hot season, 1.19% in the intermediate season, and 1.27% in the cold season, with significant differences among the 3 seasonal groups (P<0.001). These seasonal variations persisted in the subgroup analysis in each age decade (P<0.001). Conclusions: OAB-DPR varied with seasons and was significantly higher in the cold season than in the hot season, suggesting that cold weather may affect development and aggravation of OAB symptoms in men.

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