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논문 기본 정보

자료유형
학술저널
저자정보
Sungwook Chun (Department of Obstetrics and Gynecology Inje University Haeundae Paik Hospital Inje University Coll) Yong Il Ji (Department of Obstetrics and Gynecology Inje University Haeundae Paik Hospital Inje University Coll)
저널정보
대한폐경학회 대한폐경학회지 대한폐경학회지 제26권 제3호
발행연도
2020.1
수록면
159 - 164 (6page)

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초록· 키워드

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Objectives: This study aimed to evaluate the influence of simple hysterectomy on the ovarian reserve based on the type of surgery. Methods: Eighty-six premenopausal women between 31 and 48 years who underwent hysterectomy for benign gynecologic disease without additional adnexal surgery at a university hospital participated in this study. Seventy-one patients underwent laparoscopyassisted vaginal hysterectomy (LAVH), and 15 patients underwent abdominal hysterectomy (AH). Blood samples were obtained from all study participants on preoperative day and 3 days after the operation to determine the anti-Mullerian hormone (AMH) levels. Results: The postoperative reduction of the mean serum AMH level in the LAVH group (0.42 ± 0.76 ng/mL) was greater than that in the AH group, although the difference was not statistically significant (0.01 ± 0.60 ng/mL) (P = 0.053). The mean baseline AMH level (2.59 ± 2.33 ng/mL) was significantly reduced to 2.24 ± 2.08 ng/mL at 3 days after hysterectomy, and the mean rate of decline of AMH levels after surgery was 13.61% ± 30.81%. In subgroup analysis based on the type of surgery, the mean serum AMH level decreased significantly after surgery in the LAVH group, but no significant changes were found in serum AMH levels before and after the surgery in the AH group. Conclusions: These preliminary results suggest that simple hysterectomy affects the early postoperative decline of ovarian reserve, and these results might vary depending on the type of surgery.

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