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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objectives: To evaluate preoperative anti-Müllerian hormone (AMH) levels in women with endometrioma or other benign ovarian cysts and differences of AMH changes according to various characteristics. Methods: Ninety-seven patients aged 20 to 39 years who underwent surgery for benign ovarian cyst were enrolled retrospectively. Of these, 65 patients were diagnosed as endometriomas, and 32 had other benign cysts. Serum AMH, mean, maximum, and total diameter of ovarian cysts were measured. The AMH levels were compared according to pathology (endometrioma vs. other benign cyst), size of ovarian cyst, age-matched AMH quartile percentile and characteristics of endometrioma.Results: Preoperative serum AMH level was significantly lower in endometrioma group than other benign cyst group (4.12 ± 2.42 ng/mL vs. 6.02 ± 2.29 ng/mL, P < 0.001). Serum AMH level was significantly lower in endometrioma group, especially in patients aged 30 to 39 years. Dividing to age-matched AMH quartile percentile, there were significantly fewer patients with AMH level ≥ 75 percentile in endometrioma group (24.6% vs. 50.0%, P = 0.035). Among 4 subgroups of endometrioma, patients with AMH level ≥ 75 percentile were significantly decreased in multiple bilateral endometrioma group. Mean and total diameter of cysts were negatively correlated with preoperative serum AMH level in other benign cyst group.Conclusion: We suggest that preoperative AMH level measurement might be considered in women with endometrioma, especially in 30 to 39 years old, multiple bilateral type, or big-sized other benign ovarian cyst to assess the diminished ovarian reserve. (J Menopausal Med 2015;21:142-148)
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참고문헌 (23)
참고문헌 신청
ACOG Committee on Practice Bulletins. / 2000 / ACOG practice bulletin. Medical management of endometriosis. Number 11, December 1999(replaces Technical Bulletin Number 184, S
Al-Azemi M. / 2011 / Multi-marker assessment of ovarian reserve predicts oocyte yield after ovulation induction / Hum Reprod 26 : 414 ~ 422
Benaglia L. / 2009 / Endometriotic ovarian cysts negatively affect the rate of spontaneous ovulation / Hum Reprod 24 : 2183 ~ 2186
Campos CS. / 2010 / Follicular-fluid anti-Mullerian hormone concentration is similar in patients with endometriosis compared with non-endometriotic patients / Reprod Biomed
Cate RL. / 1986 / Isolation of the bovine and human genes for Mullerian inhibiting substance and expression of the human gene in animal cells / Cell 45 : 685 ~ 698
Al-Azemi M. / 2011 / Multi-marker assessment of ovarian reserve predicts oocyte yield after ovulation induction / Hum Reprod 26 : 414 ~ 422
Benaglia L. / 2009 / Endometriotic ovarian cysts negatively affect the rate of spontaneous ovulation / Hum Reprod 24 : 2183 ~ 2186
Campos CS. / 2010 / Follicular-fluid anti-Mullerian hormone concentration is similar in patients with endometriosis compared with non-endometriotic patients / Reprod Biomed
Cate RL. / 1986 / Isolation of the bovine and human genes for Mullerian inhibiting substance and expression of the human gene in animal cells / Cell 45 : 685 ~ 698
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