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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국잠사학회 International Journal of Industrial Entomology International Journal of Industrial Entomology 제41권 제2호
- 발행연도
- 2020.1
- 수록면
- 51 - 55 (5page)
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초록· 키워드
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The objective of this study was to evaluate the changes in gene expression after incubation of cells with soluble fraction from different silk mat layers. A silk cocoon from Bombyx mori was separated into 4 layers of equal thickness. The layers were numbered from 1 to 4 (from the inner to outer layer). Each silk mat was placed into normal saline and collected soluble fraction. They were administered to RAW264.7 cells, and changes in the expression of genes were evaluated by cDNA microarray analysis. Layer 1 and 4 groups showed significantly higher expression of BMP-2 at 8 h after administration of soluble fraction (P < 0.05). Runx2 expression was significantly higher in Layer 4 group at 8h (P < 0.05). The silk mat from the innermost and outermost portion of the silkworm cocoon showed a significant change in the expression of genes that are associated with osteoinduction such as BMP-2 and runx2.
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참고문헌 (19)
참고문헌 신청
Ahmad P / 2020 / Applications of bone morphogenetic proteins in dentistry : A bibliometric analysis / BiomedRes Int 2020:5971268
Edelmayer M / 2020 / Which substances loaded onto collagen scaffolds influence oral tissueregeneration?-an overview of the last 15 years / Clin Oral Investig 24(10):3363~3394
El Bialy I / 2017 / Formulation, delivery and stability of bone morphogenetic proteins for effective boneregeneration / Pharm Res 34(6):1152~1170
Jo YY / 2019 / 4-Hexylresorcinol and silk sericin increase the expression of vascular endothelial growth factorvia different pathways / Sci Rep 9:3448
Jo YY / 2017 / Bone regeneration is associated with the concentration of tumour necrosis factor-α induced by sericin released from a silk mat / Sci Rep 7:15589
Edelmayer M / 2020 / Which substances loaded onto collagen scaffolds influence oral tissueregeneration?-an overview of the last 15 years / Clin Oral Investig 24(10):3363~3394
El Bialy I / 2017 / Formulation, delivery and stability of bone morphogenetic proteins for effective boneregeneration / Pharm Res 34(6):1152~1170
Jo YY / 2019 / 4-Hexylresorcinol and silk sericin increase the expression of vascular endothelial growth factorvia different pathways / Sci Rep 9:3448
Jo YY / 2017 / Bone regeneration is associated with the concentration of tumour necrosis factor-α induced by sericin released from a silk mat / Sci Rep 7:15589
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