지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
A progressive muscle atrophy is strongly associated with aging, resulting in lower quality of life in elderly individuals. This study was conducted to determine relative hemoglobin (Hb) concentrations in the rabbit model of the sciatic nerve transection injury using non-invasive diffuse optical spectroscopy (DOS). From the 2nd week to the end of the experiment after sciatic nerve injury, a total muscle mass in nerve injured-group (NI group) significantly reduced compared with that in the normal group (p<0.001). During the capillary occlusion after nerve injury, the deoxy-hemoglobin (Hb-R) concentration in NI group significantly increased compared to that in the normal group at the 2nd and 3rd week after sciatic nerve injury (p<0.05). During the capillary release after nerve injury, the oxy-hemoglobin (Hb-O2) concentration in NI group significantly decreased at the 1st and 3rd week, and Hb-R significantly increased at 2nd week, compared to those in the normal group (p<0.05). Histological changes in the gastrocnemius muscle of NI group observed that clear fat filled spaces at the periphery of muscle fibers and angular fibers. From the results of this study, non-invasive DOS could be used to measure changes of Hb concentrations in muscles.
목차
등록된 정보가 없습니다.
참고문헌 (38)
참고문헌 신청
Barker JW / 2014 / Accuracy of oxygen saturation and total hemoglobin estimates in the neonatal brain using the semi-infinite slab model for FD-NIRS data analysis / Biomed Opt Express 5:4300~4312
Barroco AC / 2017 / A practical approach to assess leg muscle oxygenation during ramp-incremental cycle ergometry in heart failure / Braz J Med Biol Res 50:e6327
Borisov AB / 2000 / Cell death in denervated skeletal muscle is distinct from classical apoptosis / Anat Rec 258:305~318
Borisov AB / 2000 / Remodeling of the vascular bed and progressive loss of capillaries in denervated skeletal muscle / Anat Rec 258:292~304
Bosschaart N / 2014 / A literature review and novel theoretical approach on the optical properties of whole blood / Lasers Med Sci 29:453~479
Barroco AC / 2017 / A practical approach to assess leg muscle oxygenation during ramp-incremental cycle ergometry in heart failure / Braz J Med Biol Res 50:e6327
Borisov AB / 2000 / Cell death in denervated skeletal muscle is distinct from classical apoptosis / Anat Rec 258:305~318
Borisov AB / 2000 / Remodeling of the vascular bed and progressive loss of capillaries in denervated skeletal muscle / Anat Rec 258:292~304
Bosschaart N / 2014 / A literature review and novel theoretical approach on the optical properties of whole blood / Lasers Med Sci 29:453~479
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