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Effects of the Herbal Medicine in Animal Models for Treatment of Sciatic Nerve Impairment: A Review of Animal Study Reports
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좌골신경 손상에 대한 한약물 치료효과에 대한 실험논문 분석 - 국내외 한의계 연구를 중심으로 -

논문 기본 정보

Type
Academic journal
Author
Lee, Chi-ho (대전대학교 한의과대학 한방재활의학과교실) Lee, Jae-eun (대전대학교 한의과대학 한방재활의학과교실) Choi, Young-jun (부천자생한방병원 한방재활의학과) Lee, Eun-jung (대전대학교 한의과대학 한방재활의학과교실) Oh, Min-seok (대전대학교 한의과대학 한방재활의학과교실)
Journal
The Korean Academy Of Oriental Rehabilitation Medicine 한방재활의학과학회지 한방재활의학과학회지 제26권 제4호 KCI Accredited Journals
Published
2016.1
Pages
9 - 21 (13page)

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Effects of the Herbal Medicine in Animal Models for Treatment of Sciatic Nerve Impairment: A Review of Animal Study Reports
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Abstract· Keywords

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Objectives This study is to review the effect of herbal medicine on treatment of sciatic nerve injury induced animal models reported in domestic & foreign journals. Methods 5 electronic databases (Pubmed, CAJ, RISS, Oasis, Koreantk) were searched with term as sciatic nerve injury, and animal study reports on sciatic nerve impairment with herbal medicine treatment were extracted. Results 31 articles were reviewd. All studies used SD rat. 26 studies used crush injury at the sciatic nerve using haemostatic forcep and 5 studies used sciatic nerve transection. 15 studies used single herb extract and 16 studies used complex herb medicine. Angelica gigantis radix was the most frequently used herb. Each study showed significant changes of improvement indicators from sciatic nerve impairment. Conclusions Various herb medicine are expected to have positive effects on sciatic nerve impairment.
#Sciatic nerve impairment #Herb medicine #Animal model #Review

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References (61)

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Fawcett JW / 1990 / Peripheral nerve regeneration / Anne Rev Neurosci 13:42~60 google schola Dyck PJ / 1982 / The cases. Clasification and treatment of peripheral neuropathy / N Engl J Med 307:283~286 google schola Schwab ME / 1996 / Degeneration and regeneration of axons in the lesioned spinal cord / Physiol Rev 76(2):319~370 google schola Bhatheja K / 1997 / Schwann cell: Origins and role in axonal maintenance and regeneration / Mol Neurobiol 14(1-2):67~116 google schola Chen YS / 2002 / Ginsenoside Rb-1 enhance peripheral nerve regeneration across wide gaps in silicone rubber chambers / Int J Artif Organs 25(11):1103~1108 google schola

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