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논문 기본 정보

자료유형
학술저널
저자정보
Jaquelini Betta Canever (Federal University of Santa Catarina) Rafael Inacio Barbosa (Federal University of Santa Catarina) Ketlyn Germann Hendler (Federal University of Santa Catarina) Lais Mara Siqueira das Neves (Federal University of Santa Catarina) Heloyse Uliam Kuriki (Federal University of Santa Catarina) Aderbal Silva Aguiar Junior (Federal University of Santa Catarina) Marisa de Cassia Registro Fonseca (University of Sao Paulo) Alexandre Marcio Marcolino (Federal University of Santa Catarina)
저널정보
대한통증학회 The Korean Journal of Pain The Korean Journal of Pain 제34권 제3호
발행연도
2021.1
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250 - 261 (12page)

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Background: Complex regional pain syndrome type I (CRPS-I) consists of disorders caused by spontaneous pain or induced by some stimulus. The objective was to verify the effects of photobiomodulation (PBM) using 830 nm wavelength light at the affected paw and involved spinal cord segments during the warm or acute phase. Methods: Fifty-six mice were randomized into seven groups. Group (G) 1 was the placebo group; G2 and G3 were treated with PBM on the paw in the warm and acute phase, respectively; G4 and G5 treated with PBM on involved spinal cord segments in the warm and acute phase, respectively; G6 and G7 treated with PBM on paw and involved spinal cord segments in the warm and acute phase, respectively. Edema degree, thermal and mechanical hyperalgesia, skin temperature, and functional quality of gait (Sciatic Static Index [SSI] and Sciatic Functional Index [SFI]) were evaluated. Results: Edema was lower in G3 and G7, and these were the only groups to return to baseline values at the end of treatment. For thermal hyperalgesia only G3 and G5 returned to baseline values. Regarding mechanical hyperalgesia, the groups did not show significant differences. Thermography showed increased temperature in all groups on the seventh day. In SSI and SFI assessment, G3 and G7 showed lower values when compared to G1, respectively. Conclusions: PBM irradiation in the acute phase and in the affected paw showed better results in reducing edema, thermal and mechanical hyperalgesia, and in improving gait quality, demonstrating efficacy in treatment of CRPS-I symptoms.

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