Treatment of multiple gingival recessions with xenogeneic acellular dermal matrix compared to connective tissue graft: a randomized split-mouth clinical trial

Severine Vincent-Bugnas; Jonathan Laurent; Eve Naman; Mathieu Charbit; Gwenael Borie

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자료유형: 학술저널

저자정보: Severine Vincent-Bugnas (Universite Cote d'Azur Departement de Parodontologie UFR Odontologie) Jonathan Laurent (Universite Cote d'Azur Departement de Parodontologie UFR Odontologie) Eve Naman (Universite Cote d'Azur Departement de Parodontologie UFR Odontologie) Mathieu Charbit (Universite Cote d'Azur Departement de Parodontologie UFR Odontologie) Gwenael Borie (Universite Cote d'Azur Departement de Parodontologie UFR Odontologie)

저널정보: 대한치주과학회 Journal of Periodontal & Implant Science Journal of Periodontal & Implant Science 제51권 제2호

발행연도: 2021.1

수록면: 77 - 87 (11page)

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Purpose: The aim of this study was to compare the efficacy of the tunnel technique for root coverage using a new xenogeneic acellular dermal matrix vs. connective tissue grafting (CTG) for the treatment of multiple maxillary adjacent recessions (recession type 1) at 12 months postoperatively. Methods: This study enrolled 12 patients with at least 3 contiguous, bilateral, symmetrical maxillary gingival recessions (i.e., at least 6 recessions per patient). In total, 74 recessions were treated using the modified coronally advanced tunnel (MCAT) technique combined with a novel porcine-derived acellular dermal matrix (PADM) at 37 test sites or CTG at 37 control sites. The following clinical parameters were measured: recession height, clinical attachment level, width of keratinized tissue, probing depth, recession width, gingival thickness, mean root coverage (MRC), and complete root coverage (CRC). Comparisons between test and control groups were made for pain visual analog scale scores at 14 days. Results: At 12 months, the MCAT with PADM (test) yielded a statistically significant improvement in all clinical parameters studied. MRC was significantly higher on the control sides (80.6%±23.7%) than on the test sides (68.8%±23.4%). Similarly, CRC was 48.7%±6.8% on the control sides (CTG), in contrast to 24.3%±8.2% on the test sides (PADM). Statistically significant differences were observed in favor of the control sides for all clinical parameters studied. Nevertheless, the MCAT in adjunction with PADM was clearly superior at reducing mean and maximum patient-reported postoperative pain intensity and pain duration in the first week after surgery. Conclusions: The use of PADM to treat multiple recessions improved clinical parameters at 12 months, but these outcomes were nevertheless poorer than those observed for CTG. However, PADM reduced morbidity, particularly the pain experienced by patients. Trial Registration: ClinicalTrials.gov Identifier: NCT03162016

#Acellular dermis #Connective tissue #Gingival recession #Oral surgical procedures

참고문헌 (30)

참고문헌 신청

Zucchelli G / 2020 / Autogenous soft tissue grafting for periodontal and peri-implant plastic surgical reconstruction / J Periodontol 91:9~16

Chambrone L / 2018 / Root coverage procedures for treating localised and multiple recession-type defects / Cochrane Database Syst Rev 10:CD007161

Tonetti MS / 2018 / Xenogenic collagen matrix or autologous connective tissue graft as adjunct to coronally advanced flaps for coverage of multiple adjacent gingival recession : randomized trial assessing non-inferiority in root coverage and superiority in oral health-related quality of life / J Clin Periodontol 45:78~88

Aguirre-Zorzano LA / 2017 / Complications of harvesting a connective tissue graft from the palate. A retrospective study and description of a new technique / J Clin Exp Dent 9:e1439~45

Griffin TJ / 2006 / Postoperative complications following gingival augmentation procedures / J Periodontol 77:2070~2079

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