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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한악안면성형재건외과학회 Maxillofacial Plastic Reconstructive Surgery Maxillofacial Plastic Reconstructive Surgery 제42권 제8호
- 발행연도
- 2020.1
- 수록면
- 1 - 6 (6page)
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초록· 키워드
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Background: Orofacial clefts (OFCs) comprise a wide range of malformations, including cleft lip, cleft palate, and cleft lip with cleft palate, which can vary in terms of etiology, severity, and disease burden. Objective(s): This study aimed to evaluate the correlation between various risk factors and orofacial cleft disorder spectrum in newborns. Study design: A total of 323 cases and 400 controls were enrolled in this study and evaluated in terms of the maternal history of abortion or miscarriage, child’s sex, maternal and paternal age, maternal history of systemic disease, history of medication therapy during pregnancy, birth order, consanguineous marriage, and complications during pregnancy. Results: Analysis of the results suggested that consanguineous marriage, a maternal history of abortion/miscarriage, and complications during pregnancy could potentially increase the risk of OFCs in children (P < 0.05). However, the analyses revealed that the other variables could not potentially increase the risk of OFCs (P > 0.05). Conclusion(s): Multiple cofactors may simultaneously contribute to the formation of such abnormalities; therefore, a comprehensive, multidisciplinary care program is necessary to ensure a successful pregnancy period and the birth of a healthy newborn.
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참고문헌 (44)
참고문헌 신청
Pereira AV / 2018 / Associated malformations in children with orofacial clefts in Portugal:a 31-year study / Plast Reconstr Surg Glob Open 6(2)
Eshete M / 2020 / The role of environmental factors in the etiology of nonsyndromic orofacial clefts / J Craniofacial Surg 31(1):113~116
Moreno Uribe L / 2017 / A population-based study of effects of genetic loci on orofacial clefts / J Dent Res 96(11):1322~1329
Saleem K / 2019 / Assessment of candidate genes and genetic heterogeneity in human non syndromic orofacial clefts specifically non syndromic cleft lip with or without palate / Heliyon 5(12):e03019
Raut JR / 2019 / Proportion of orofacial clefts attributable to recognized risk factors / Cleft Palate-Craniofacial J 56(2):151~158
Eshete M / 2020 / The role of environmental factors in the etiology of nonsyndromic orofacial clefts / J Craniofacial Surg 31(1):113~116
Moreno Uribe L / 2017 / A population-based study of effects of genetic loci on orofacial clefts / J Dent Res 96(11):1322~1329
Saleem K / 2019 / Assessment of candidate genes and genetic heterogeneity in human non syndromic orofacial clefts specifically non syndromic cleft lip with or without palate / Heliyon 5(12):e03019
Raut JR / 2019 / Proportion of orofacial clefts attributable to recognized risk factors / Cleft Palate-Craniofacial J 56(2):151~158
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