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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 38 - 47 (10page)
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초록· 키워드
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The prevalence of pancreatic cystic lesions (PCLs) has increased recently due to the increased use of cross-sectional abdominalimaging and the ageing global population. Current diagnostic techniques are inadequate to distinguish between PCLs thatrequire surgery, close surveillance, or expectant management. This has resulted in increased morbidity from both inappropriatelyaggressive and conservative management strategies. Needle-based confocal laser endomicroscopy (nCLE) has allowed microscopicexamination and visual delineation of the surface epithelium of PCLs. Landmark studies in this decade have correlated nCLE andhistological findings and identified characteristics differentiating various types of PCLs. Subsequent studies have confirmed thehigh diagnostic yield of nCLE and its diagnostic utility in PCLs with an equivocal diagnosis. Moreover, nCLE has been shown toimprove the diagnostic yield of PCLs. This will help avoid unnecessary pancreatic surgery, which carries significant morbidity andmortality risks. The early detection of high-grade dysplasia in PCLs will provide early surgical treatment and improve outcomes forpancreatic cancer. Despite the high upfront cost of nCLE, the improved diagnostic accuracy and resultant appropriate managementhave resulted in improved cost effectiveness. Refining the procedure technique and limiting the procedure length have significantlyimproved the safety of nCLE. A structured training program and device improvements to allow more complete mapping of thepancreatic cyst epithelium will be crucial for the widespread adoption of this promising technology.
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참고문헌 (33)
참고문헌 신청
Laffan TA / 2008 / Prevalence of unsuspected pancreatic cysts on MDCT / AJR Am J Roentgenol 191:802~807
de Jong K / 2012 / Epidemiology, diagnosis, and management of cystic lesions of the pancreas / Gastroenterol Res Pract 2012:147465
de Jong K / 2010 / High prevalence of pancreatic cysts detected by screening magnetic resonance imaging examinations / Clin Gastroenterol Hepatol 8:806~811
Nougaret S / 2016 / Cystic pancreatic lesions : from increased diagnosis rate to new dilemmas / Diagn Interv Imaging 97:1275~1285
Tanaka M / 2006 / International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas / Pancreatology 6:17~32
de Jong K / 2012 / Epidemiology, diagnosis, and management of cystic lesions of the pancreas / Gastroenterol Res Pract 2012:147465
de Jong K / 2010 / High prevalence of pancreatic cysts detected by screening magnetic resonance imaging examinations / Clin Gastroenterol Hepatol 8:806~811
Nougaret S / 2016 / Cystic pancreatic lesions : from increased diagnosis rate to new dilemmas / Diagn Interv Imaging 97:1275~1285
Tanaka M / 2006 / International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas / Pancreatology 6:17~32
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