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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 92 - 98 (7page)
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초록· 키워드
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Background: This study investigated the prevalence and impact of 25-hydroxyvitamin D (25(OH) vitamin D) deficiency in critically ill Korean patients with traumatic injuries. Methods: This prospective observational cohort study assessed the 25(OH) vitamin D status of consecutive trauma patients admitted to the trauma intensive care unit (TICU) of Kyungpook National University Hospital between January and December 2018. We analyzed the prevalence of 25(OH) vitamin D deficiency and its impact on clinical outcomes. Results: There were no significant differences in the duration of mechanical ventilation (MV), lengths of TICU and hospital stays, and rates of nosocomial infection and mortality between patients with 25(OH) vitamin D <20 ng/ml and those with 25(OH) vitamin D ≥20 ng/ml within 24 hours of TICU admission. The duration of MV and lengths of TICU and hospital stays were shorter and the rate of nosocomial infection was lower in patients with 25(OH) vitamin D level ≥20 ng/ml on day 7 of hospitalization. The duration of MV, lengths of TICU and hospital stays, and nosocomial infection rate were significantly lower in patients with increased concentrations compared with those with decreased concentrations on day 7 of hospitalization, but the mortality rate did not differ significantly. Conclusions: The 25(OH) vitamin D level measured within 24 hours after TICU admission was unrelated to clinical outcomes in critically ill patients with traumatic injuries. However, patients with increased 25(OH) vitamin D level after 7 days of hospitalization had better clinical outcomes than those with decreased levels.
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참고문헌 (19)
참고문헌 신청
Choi HS / 2011 / Vitamin D insufficiency in Korea : a greater threat to younger generation : the Korea National Health and Nutrition Examination Survey(KNHANES)2008 / J Clin Endocrinol Metab 96:643~651
Schwalfenberg GK / 2011 / A review of the critical role of vitamin D in the functioning of the immune system and the clinical implications of vitamin D deficiency / Mol Nutr Food Res 55:96~108
Jeng L / 2009 / Alterations in vitamin D status and anti-microbial peptide levels in patients in the intensive care unit with sepsis / J Transl Med 7:28
Holick MF / 2011 / Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline / J Clin Endocrinol Metab 96:1911~1930
Lee P / 2009 / Vitamin D deficiency in the intensive care unit: an invisible accomplice to morbidity and mortality? / Intensive Care Med 35:2028~2032
Schwalfenberg GK / 2011 / A review of the critical role of vitamin D in the functioning of the immune system and the clinical implications of vitamin D deficiency / Mol Nutr Food Res 55:96~108
Jeng L / 2009 / Alterations in vitamin D status and anti-microbial peptide levels in patients in the intensive care unit with sepsis / J Transl Med 7:28
Holick MF / 2011 / Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline / J Clin Endocrinol Metab 96:1911~1930
Lee P / 2009 / Vitamin D deficiency in the intensive care unit: an invisible accomplice to morbidity and mortality? / Intensive Care Med 35:2028~2032
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