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논문 기본 정보

자료유형
학술저널
저자정보
김다희 (단국대학교 치위생학과) 강미선 ((주)오라덴틱스) 여지은 ((주)오라덴틱스) 이명구 (건국대학교) 조자원 (단국대학교)
저널정보
대한예방치과·구강보건학회 대한구강보건학회지 대한구강보건학회지 제44권 제4호
발행연도
2020.1
수록면
246 - 252 (7page)

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Objectives: Previous studies have suggested that the lactic acid bacterium, Weissella cibaria CMU has beneficial effects on halitosis, but its precise effects have not been evaluated in human subjects. We evaluated the efficacy and safety of W. cibaria CMU for reducing halitosis in adults (20-70 years old) whose exhibited volatile sulfur compound (VSC) concentrations exceeded 0.015 ng/mL and who scored ≥2 points in a halitosis sensory evaluation test. Methods: A total of 60 participants were assigned to an experimental group (treated with W. cibaria CMU) and a control group (placebo). In total, 58 out of 60 participants (experimental group, 29; control group, 29) were ultimately included in gas chromatography (OralChroma) analyses of VSC concentrations and halitosis sensory evaluation tests. Results: We found that the VSC concentration decreased by 0.030±0.062 ng/ml in the experimental group after 8 weeks (P =0.0138) and increased by 0.005±0.124 ng/ml in the control group (P =0.8198). However, the difference between groups was not statistically significant (P>0.05). In a sensory evaluation test, a significantly lower score was obtained for the experimental group than for the control group. Conclusions: Overall, VSC concentrations and sensory evaluation scores were lower in the experimental group than in the control group, but only the latter was statistically significant. Thus, we conclude that W. cibaria CMU is involved in the reduction of halitosis.

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