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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 32 - 38 (7page)
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초록· 키워드
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Tubulysins are a group of secondary metabolites produced by myxobacteria that inhibit the function of the eukayotic cytoskeleton. We developed a pair of PCR primers that specifically amplified tubulysin biosynthetic genes. Using these primers, eight out of the eighty-one strains of myxobacteria belonging to the Cystobacteraceae family that harbored putative tubulysin biosynthetic genes were screened through PCR analysis. The selected strains included two Archangium gephyra, two Stigmatella sp., two Vitiosangium cumulatum, and two unidentified myxobacteria. LC-MS analysis of the culture extracts from the selected strains revealed that A. gephyra KYC4066 produced putative tubulysin A and B.
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등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Gerth K / 2003 / Myxobacteria : proficient producers of novel natural products with various biological activities—past and future biotechnological aspects with the focus on the genus Sorangium / J. Biotechol 106:233~253
Schaberle TF / 2014 / Antibiotics from myxobacteria / Nat. Prod. Rep 31:953~972
현혜숙 / 2018 / 점액세균의 이차대사산물 / 미생물학회지 54(3):175~187
Gerth K / 1996 / Epothilons A and B: antifungal and cytotoxic compounds from Sorangium cellulosum (Myxobacteria). Production, physicochemical and biological properties / J. Antibiot 49:560~563
Stein A / 2010 / Ixabepilone / Clin. J. Oncol. Nurs 14:65~71
Schaberle TF / 2014 / Antibiotics from myxobacteria / Nat. Prod. Rep 31:953~972
현혜숙 / 2018 / 점액세균의 이차대사산물 / 미생물학회지 54(3):175~187
Gerth K / 1996 / Epothilons A and B: antifungal and cytotoxic compounds from Sorangium cellulosum (Myxobacteria). Production, physicochemical and biological properties / J. Antibiot 49:560~563
Stein A / 2010 / Ixabepilone / Clin. J. Oncol. Nurs 14:65~71
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