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논문 기본 정보

자료유형
학술저널
저자정보
Katharina Feil (Department of Neurology Ludwig Maximilian University (LMU) Munich Germany) Moriz Herzberg (Institute of Neuroradiology Ludwig Maximilian University (LMU) Munich Germany) Franziska Dorn (Institute of Neuroradiology Ludwig Maximilian University (LMU) Munich Germany) Steffen Tiedt (Institute for Stroke and Dementia Research Ludwig Maximilian University (LMU) Munich Germany) Clemens Kupper (Department of Neurology Ludwig Maximilian University (LMU) Munich Germany) Dennis C. Thunstedt (Department of Neurology Ludwig Maximilian University (LMU) Munich Germany) Ludwig C. Hinske (Department of Anesthesiology Ludwig Maximilian University (LMU) Munich Germany) Konstanze Muhlbauer (Department of Anesthesiology Ludwig Maximilian University (LMU) Munich Germany) Sebastian Goss (Department of Anesthesiology Ludwig Maximilian University (LMU) Munich Germany) Thomas Liebig (Institute of Neuroradiology Ludwig Maximilian University (LMU) Munich Germany) Marianne Dieterich (Department of Neurology Ludwig Maximilian University (LMU) Munich Germany) Andreas Bayer (Department of Anesthesiology Ludwig Maximilian University (LMU) Munich Germany) Lars Kellert (Department of Neurology Ludwig Maximilian University (LMU) Munich Germany)
저널정보
대한뇌졸중학회 대한뇌졸중학회지 대한뇌졸중학회지 제23권 제1호
발행연도
2021.1
수록면
103 - 112 (10page)

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Background and Purpose: Anesthesia regimen in patients undergoing mechanical thrombectomy (MT) is still an unresolved issue. Methods: We compared the effect of anesthesia regimen using data from the German StrokeRegistry- Endovascular Treatment (GSR-ET) between June 2015 and December 2019. Degreeof disability was rated by the modified Rankin Scale (mRS), and good outcome was defined as mRS 0?2. Successful reperfusion was assumed when the modified thrombolysis in cerebral infarction scale was 2b?3. Results: Out of 6,635 patients, 67.1% (n=4,453) patients underwent general anesthesia (GA), 24.9% (n=1,650) conscious sedation (CS), and 3.3% (n=219) conversion from CS to GA. Rate of successful reperfusion was similar across all three groups (83.0% vs. 84.2% vs. 82.6%, P=0.149). Compared to the CA-group, the GA-group had a delay from admission to groin (71.0 minutes vs. 61.0 minutes, P<0.001), but a comparable interval from groin to flow restoration (41.0 minutes vs. 39.0 minutes). The CS-group had the lowest rate of periprocedural complications (15.0% vs. 21.0% vs. 28.3%, P<0.001). The CS-group was more likely to have a good outcome at follow-up (42.1% vs. 34.2% vs. 33.5%, P<0.001) and a lower mortality rate (23.4% vs. 34.2% vs. 26.0%, P<0.001). In multivariable analysis, GA was associated with reduced achievement of good functional outcome (odds ratio [OR], 0.82; 95% confidence interval [CI], 0.71 to 0.94; P=0.004) and increased mortality (OR, 1.42; 95% CI, 1.23 to 1.64; P<0.001). Subgroup analysis for anterior circulation strokes (n=5,808) showed comparable results. Conclusions: We provide further evidence that CS during MT has advantages over GA in terms of complications, time intervals, and functional outcome.

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