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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 205 - 205 (1page)
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Juxtaposed with another zinc finger protein 1 (JAZF1) is associated with metabolic disorders, including type 2 diabetes mellitus (T2DM). Several studies showed that JAZF1 and body fat mass are closely related. We attempted to elucidate the JAZF1 functions on adipose development and related metabolism using in vitro and in vivo models. The JAZF1 expression was precisely regulated during adipocyte differentiation of 3T3L1 preadipocyte and mouse embryonic fibroblasts (MEFs). Homozygous JAZF1 deletion (JAZF1-KO) also resulted in impaired adipocyte differentiation in MEF. The JAZF1 role in adipocyte differentiation regulation was demonstrated by ... 전체 초록 보기
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