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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 179 - 179 (1page)
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In recent years, many researchers reported that therapeutic effect of stem cells for diverse diseases. However, unlike other tissue, brain has specific structure, called synapse. The synapses not only transmit, but also process and refine information. Therefore, synaptic regeneration is a key role for therapy of neurodegenerative disorders. Neurexins (NRXN) and neuroligins (NLGN) are synaptic cell-adhesion molecules that connect pre- and postsynaptic neurons at synapses, mediate trans-synaptic signaling, and shape neural network properties by specifying synaptic functions. In this study, we investigated to synaptic regeneration effect of human neural stem cells over-expressing NRXN (F3.NRXN) and NLGN (F3.NLGN) a spinal cord injury model. Over-expressing NRXN and NLGN in the neural stem cells upregulated expression of synaptophysin, ... 전체 초록 보기
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