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자료유형
학술대회자료
저자정보
Jong Eun Lee (Soonchunhyang University Hospital)
저널정보
대한종양외과학회 대한임상종양학회 학술대회지 대한종양외과학회 2021 Seoul International Symposium of Surgical Oncology [초록집]
발행연도
2021.6
수록면
44 - 45 (2page)

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Human beings are suffering from various diseases in their lives, and at that times when science was not developed, they also believed that they were sick from evil energy or soul. Gradually, as science developed, the causes of various diseases were revealed and the treatments began to be developed. People have tried to understand the cell level, which is the basic unit of human beings, and various methods have been developed to understand them. Cell staining was developed and expanded through microscopy. After that, the gene level was reached in the nucleic acid.

In medicine, constant research is being done to understand and treat diseases through genetic analysis of humans. In 2006, the TCGA project was launched to understand the molecular biological basis of cancer through genome analysis technology, collecting data such as diagnosis, treatment, pathology, tumorigenesis, gene expression, RNA sequence, chromosome number, tumor quality, DNA metallization pattern, miRNA expression, DNA sequence, protein expression, and various imaging information. Currently, about 23,000 genes and 3.5 million mutations are analyzed through 84,000 cases for about 30 types of cancer. This analysis showed that even cancer developed in the same site had different progression processes, different prognosis, and different treatment methods. The vast amount of research that could be done was made possible by the development of various analytical methods that could be analyzed at the molecular level.

In 1970s, direct nucleotide sequence analysis method developed by Sanger was traditionally used, which is deoxynucleotide (dNTP) that allows DNA replication enzymes to continue to synthesize DNA strands during D ... 전체 초록 보기

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