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논문 기본 정보

자료유형
학술대회자료
저자정보
In Ja Park (Asan Medical Center)
저널정보
대한종양외과학회 대한임상종양학회 학술대회지 대한종양외과학회 2021 Seoul International Symposium of Surgical Oncology [초록집]
발행연도
2021.6
수록면
40 - 41 (2page)

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Neoadjuvant chemoradiotherapy followed by total mesorectal excision has represented standard treatment for locally advanced rectal cancer and adjuvant chemotherapy because it was proved to reduce local recurrence significantly. The majority of patients with locally advanced rectal cancer, however, still suffer distant metastasis. Indeed, advances in local control have not translated into overall survival improvement. Current treatment modalities are also challenged in terms of tumor response. Tumor response to radiation therapy would progress further with longer interval to definite treatment or evaluation. However, based on its initial advanced stage, just wait without any treatment impose risk of disease progression. Addition of additional chemotherapy would be proposed to facilitate prolong waiting period.

One of the issues with current rectal cancer treatment scheme has been poor compliance with adjuvant chemotherapy. Chronicle study reported that only 48% of patients with stage III rectal cancer completed 6 cycles adjuvant XELOX. EORTC 22921 showed that less than 43% of patients with stage II/III rectal cancer completed adjuvant 5FU-based chemotherapy. To solve poor compliance, administration the whol^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10593427');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#

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