지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.5
- 수록면
- 188 - 189 (2page)
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초록· 키워드
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Purpose
The restorative total proctocolectomy (TPC) procedure has significantly reduced the lifetime colorectal cancer risk in familial adenomatous polyposis (FAP) patients. However, adenomas may develop in the ileal pouch over time and may even progress to carcinoma. We here evaluated the cumulative incidence, time to development, and risk factors associated with this.
Methods
We enrolled 95 FAP patients who underwent TPC and ileal pouch anal anastomosis (IPAA) at Asan Medical Center between 1989 and 2018. Demographic data, details of surgery, details of follow-up pouch endoscopy, and pathologic findings were retrospectively collected.
Results
The mean follow-up period was 88 months. Pouch adenomas were found in 24 (22.9%) cases with a median time of 52 months to their first formation (IQR, 28.3-114.3 mo). Tubular adenomas were detected in most patients (95.9%). There were no high-grade dysplasias or malignancies. Of the 24 patients with pouch adenoma, 13 pa^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10577855');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#
The restorative total proctocolectomy (TPC) procedure has significantly reduced the lifetime colorectal cancer risk in familial adenomatous polyposis (FAP) patients. However, adenomas may develop in the ileal pouch over time and may even progress to carcinoma. We here evaluated the cumulative incidence, time to development, and risk factors associated with this.
Methods
We enrolled 95 FAP patients who underwent TPC and ileal pouch anal anastomosis (IPAA) at Asan Medical Center between 1989 and 2018. Demographic data, details of surgery, details of follow-up pouch endoscopy, and pathologic findings were retrospectively collected.
Results
The mean follow-up period was 88 months. Pouch adenomas were found in 24 (22.9%) cases with a median time of 52 months to their first formation (IQR, 28.3-114.3 mo). Tubular adenomas were detected in most patients (95.9%). There were no high-grade dysplasias or malignancies. Of the 24 patients with pouch adenoma, 13 pa^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10577855');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#
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